Literature DB >> 6292049

The human serum albumin gene: structure of a unique locus.

J W Hawkins, A Dugaiczyk.   

Abstract

The entire gene for human serum albumin (HSA) has been isolated from a genomic DNA library, carried in the lambda Charon 4A vector. Six independent isolates have been found to hybridize to a cloned HSA cDNA probe, and all six clones share restriction site sequence homology in the overlapping portion of their DNA. These results seem to indicate that the albumin gene is single-copy, or unique, within the human haploid genome. Measuring from the "CAP" site to the "poly(A)" addition site, albumin gene comprises 16.5 kb of DNA.

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Year:  1982        PMID： 6292049     DOI： 10.1016/0378-1119(82)90188-3

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  10 in total

1.  Amino acid substitutions in genetic variants of human serum albumin and in sequences inferred from molecular cloning.

Authors:  N Takahashi; Y Takahashi; B S Blumberg; F W Putnam
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

2.  Polymorphisms of human albumin gene after DNA restriction by HaeIII endonuclease.

Authors:  S L de Souza; M Frain; E Mornet; J M Sala-Trépat; G Lucotte
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

3.  Linkage of the evolutionarily-related serum albumin and alpha-fetoprotein genes within q11-22 of human chromosome 4.

Authors:  M E Harper; A Dugaiczyk
Journal:  Am J Hum Genet       Date:  1983-07       Impact factor: 11.025

4.  Molecular genetics of human serum albumin: restriction enzyme fragment length polymorphisms and analbuminemia.

Authors:  J C Murray; C M Demopulos; R M Lawn; A G Motulsky
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

Review 5.  Review: modifications of human serum albumin and their binding effect.

Authors:  Philbert Lee; Xiaoyang Wu
Journal:  Curr Pharm Des       Date:  2015       Impact factor: 3.116

6.  Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.

Authors:  Karolina A Majorek; Przemyslaw J Porebski; Arjun Dayal; Matthew D Zimmerman; Kamila Jablonska; Alan J Stewart; Maksymilian Chruszcz; Wladek Minor
Journal:  Mol Immunol       Date:  2012-06-06       Impact factor: 4.407

7.  Nonrandom gene organization: structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains.

Authors:  Y Xing; C V Johnson; P T Moen; J A McNeil; J Lawrence
Journal:  J Cell Biol       Date:  1995-12       Impact factor: 10.539

Review 8.  Allergy to uncommon pets: new allergies but the same allergens.

Authors:  Araceli Díaz-Perales; David González-de-Olano; Marina Pérez-Gordo; Carlos Pastor-Vargas
Journal:  Front Immunol       Date:  2013-12-30       Impact factor: 7.561

9.  Albumin is an interface between blood plasma and cell membrane, and not just a sponge.

Authors:  Jens van de Wouw; Jaap A Joles
Journal:  Clin Kidney J       Date:  2021-10-05

Review 10.  Unraveling the mysteries of serum albumin-more than just a serum protein.

Authors:  Angelica M Merlot; Danuta S Kalinowski; Des R Richardson
Journal:  Front Physiol       Date:  2014-08-12       Impact factor: 4.566
  10 in total

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