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Literature DB >> 6291047

Detection and cloning of human DNA sequences related to the mouse mammary tumor virus genome.

R Callahan, W Drohan, S Tronick, J Schlom.

Abstract

Sequences related to the mouse mammary tumor virus (MMTV) genome have been detected in fragments of restricted human cellular DNA. These results were obtained by using recombinant DNA containing the MMTV proviral genome and lowering the stringency of blot-hybridization conditions. The MMTV genome also reacts with unique families of fragments in restricted cellular DNA from other mammalian species but not with salmon sperm DNA. A clone that reacted with labeled MMTV proviral DNA was selected from a human DNA library in Charon 4A. Under stringent conditions, a 3.7-kilobase MMTV-related EcoRI fragment of this clone hybridized with many of the same EcoRI restriction fragments of human cellular DNA detectable with MMTV proviral DNA under low-stringency conditions. Specific fragments of the human clone were shown to contain sequences related to the molecularly cloned gag, pol, and env regions of the MMTV genome.

Entities: Gene Species

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Year: 1982 PMID： 6291047 PMCID： PMC346932 DOI： 10.1073/pnas.79.18.5503

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

31 in total

1. Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates.

Authors: D H Spector; H E Varmus; J M Bishop
Journal: Proc Natl Acad Sci U S A Date: 1978-09 Impact factor: 11.205

2. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors: E M Southern
Journal: J Mol Biol Date: 1975-11-05 Impact factor: 5.469

3. Comparison of mouse mammary tumor virus-specific DNA in inbred, wild and Asian mice, and in tumors and normal organs from inbred mice.

Authors: V L Morris; E Medeiros; G M Ringold; J M Bishop; H E Varmus
Journal: J Mol Biol Date: 1977-07 Impact factor: 5.469

4. Detection in human breast carcinomas of an antigen immunologically related to a group-specific antigen of mouse mammary tumor virus.

Authors: R Mesa-Tejada; I Keydar; M Ramanarayanan; T Ohno; C Fenoglio; S Spiegelman
Journal: Proc Natl Acad Sci U S A Date: 1978-03 Impact factor: 11.205

5. Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors: P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal: J Mol Biol Date: 1977-06-15 Impact factor: 5.469

6. Isolation of host-range variants of mouse mammary tumor viruses that efficiently infect cells in vitro.

Authors: D K Howard; J Schlom
Journal: Proc Natl Acad Sci U S A Date: 1978-11 Impact factor: 11.205

7. Homology between human breast tumour RNA and mouse mammary tumour virus genome.

Authors: A B Vaidya; M M Black; A S Dion; D H Moore
Journal: Nature Date: 1974-06-07 Impact factor: 49.962

8. Presence in human breast cancer of RNA homologous to mouse mammary tumour virus RNA.

Authors: R Axel; J Schlom; S Spiegelman
Journal: Nature Date: 1972-01-07 Impact factor: 49.962

9. Isolation of high-molecular-weight DNA from mammalian cells.

Authors: M Gross-Bellard; P Oudet; P Chambon
Journal: Eur J Biochem Date: 1973-07-02

10. Of birds and mice and men: comments on the use of animal models and molecular hybridization in the search for human tumor viruses.

Authors: J M Bishop; N Quintrell; E Medeiros; H E Varmus
Journal: Cancer Date: 1974-10 Impact factor: 6.860

38 in total

1. Isolation of three kinds of human endogenous retrovirus-like sequences using tRNA(Pro) as a probe.

Authors: F Harada; N Tsukada; N Kato
Journal: Nucleic Acids Res Date: 1987-11-25 Impact factor: 16.971

2. Molecular cloning and long terminal repeat sequences of human endogenous retrovirus genes related to types A and B retrovirus genes.

Authors: M Ono
Journal: J Virol Date: 1986-06 Impact factor: 5.103

3. Detection and cloning of new HTLV-related endogenous sequences in man.

Authors: A Perl; J D Rosenblatt; I S Chen; J P DiVincenzo; R Bever; B J Poiesz; G N Abraham
Journal: Nucleic Acids Res Date: 1989-09-12 Impact factor: 16.971

4. Detection of multiple, novel reverse transcriptase coding sequences in human nucleic acids: relation to primate retroviruses.

Authors: A Shih; R Misra; M G Rush
Journal: J Virol Date: 1989-01 Impact factor: 5.103

10. Characterization of novel reverse transcriptase encoding human endogenous retroviral sequences similar to type A and type B retroviruses: differential transcription in normal human tissues.

Authors: P Medstrand; J Blomberg
Journal: J Virol Date: 1993-11 Impact factor: 5.103