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Literature DB >> 6289732

Inconsistency of synergy between the beta-lactamase inhibitor CP-45,899 and beta-lactam antibiotics against multiply drug-resistant Enterobacteriaceae and pseudomonas species.

Abstract

Synergy between CP-45,899 and ampicillin or newer beta-lactam antibiotics against multiply drug-resistant Enterobacteriaceae and Pseudomonas species was inconsistent. In contrast, synergy between CP-45,899 and ampicillin against beta-lactamase-producing strains of Haemophilus influenzae type b and Bacteroides fragilis was consistent and marked.

Entities: Chemical Species

Mesh：

Substances：

Year: 1981 PMID： 6289732 PMCID： PMC181432 DOI： 10.1128/AAC.19.2.361

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. CP-45,899, a beta-lactamase inhibitor that extends the antibacterial spectrum of beta-lactams: initial bacteriological characterization.

Authors: A R English; J A Retsema; A E Girard; J E Lynch; W E Barth
Journal: Antimicrob Agents Chemother Date: 1978-09 Impact factor: 5.191

Review 2. The beta-lactamases of gram-negative bacteria and their role in resistance to beta-lactam antibiotics.

Authors: R B Sykes; M Matthew
Journal: J Antimicrob Chemother Date: 1976-06 Impact factor: 5.790

3. Activity of beta-lactamase produced by Bacteroides fragilis against newly introduced cephalosporins.

Authors: K Sato; M Inoue; S Mitsuhashi
Journal: Antimicrob Agents Chemother Date: 1980-04 Impact factor: 5.191

4. Factors contributing to resistance to beta-lactam antibiotics in Bacteroides fragilis.

Authors: B Olsson; K Dornbusch; C E Nord
Journal: Antimicrob Agents Chemother Date: 1979-02 Impact factor: 5.191

5. In vitro antimicrobial activity of cefoperazone, cefotaxime, moxalactam (LY127935), azlocillin, mezlocillin, and other beta-lactam antibiotics against Neisseria gonorrhoeae and Haemophilus influenzae, including beta-lactamase-producing strains.

Authors: C N Baker; C Thornsberry; R N Jones
Journal: Antimicrob Agents Chemother Date: 1980-04 Impact factor: 5.191

6. Interaction of clindamycin and gentamicin in vitro.

Authors: R J Fass; C A Rotilie; R B Prior
Journal: Antimicrob Agents Chemother Date: 1974-11 Impact factor: 5.191

7. Comparative inhibition beta-lactamases by novel beta-lactam compounds.

Authors: K P Fu; H C Neu
Journal: Antimicrob Agents Chemother Date: 1979-02 Impact factor: 5.191

8. A sulfone beta-lactam compound which acts as a beta-lactamase inhibitor.

Authors: N Aswapokee; H C Neu
Journal: J Antibiot (Tokyo) Date: 1978-12 Impact factor: 2.649

9. CP-45,899 in combination with penicillin or ampicillin against penicillin-resistant Staphylococcus, Haemophilus influenzae, and Bacteroides.

Authors: J A Retsema; A R English; A E Girard
Journal: Antimicrob Agents Chemother Date: 1980-04 Impact factor: 5.191

10. In vitro activity of LY127935.

Authors: R J Fass
Journal: Antimicrob Agents Chemother Date: 1979-10 Impact factor: 5.191

4 in total

1. In vitro activities of cefoperazone and sulbactam singly and in combination against cefoperazone-resistant members of the family Enterobacteriaceae and nonfermenters.

Authors: R J Fass; W W Gregory; R F D'Amato; J M Matsen; D N Wright; L S Young
Journal: Antimicrob Agents Chemother Date: 1990-11 Impact factor: 5.191