Literature DB >> 628937

[The place of radiation therapy in the treatment of giant cell tumors of bone (osteoclastomas): results from 32 cases (author's transl)].

C Glanzmann, W Horst.   

Abstract

Radiotherapeutic results of giant-cell tumors of the bone in 32 own cases are presented. The frequency of local recurrency was 30%, the 10-year survival rate was somewhat about 70% and in nearly 12% of primary benign giant-cell tumors there appeared malignant transformations (inclusive two fibrosarcomas in irradiated tissue). In other radiotherapeutic series, the frequency of malignant transformation is between 14 and 19%, in series with primary surgical therapy the rate of secundary malignant transformation is between 3 and 10%. Despite of the limited comparability of the surgical and radiotherapeutic material, we recommend in accordance with most authors in operable lesions surgical treatment. In inoperable lesions or when the lesion is not radically operable, radiation therapy has a definite place in the treatment of giant-cell tumors of the bone with a curative rate of about 80%.

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Year:  1978        PMID: 628937

Source DB:  PubMed          Journal:  Strahlentherapie        ISSN: 0039-2073


  2 in total

1.  Application of free autogenous fibular graft in the treatment of aggressive bone tumours of the distal end of the radius.

Authors:  P Salenius; S Santavirta; O Kiviluoto; E V Koskinen
Journal:  Arch Orthop Trauma Surg       Date:  1981

2.  [Operative therapy of benign and semimalignant bone tumors].

Authors:  E Morscher
Journal:  Langenbecks Arch Chir       Date:  1982
  2 in total

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