Literature DB >> 6289062

In vitro stimulation of lymphocytes by different strains of cytomegalovirus.

L Gärtner, J A Wilhelm, R Czieschnek.   

Abstract

The in vitro stimulation of lymphocytes from 15 healty adult donors by 5 different stains of CMV resulted in a positive stimulation ratio of lymphocytes from CMV seropositive donors with each of the 5 different strains. Differences in the absolute strength of the response was observed among the 5 strains for each individual, but we concluded that the use of antigen prepared with 1 strain of CMV is sufficient to obtain a positive or negative result. A maximum value for the in vitro lymphocyte stimulation test, however, will only be obtained using different antigen concentrations from several different CMV strains simultaneously.

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Year:  1982        PMID: 6289062     DOI: 10.1007/bf02122707

Source DB:  PubMed          Journal:  Med Microbiol Immunol        ISSN: 0300-8584            Impact factor:   3.402


  14 in total

1.  Cell-mediated immunity to cytomegalovirus in immunocompromised patients: effect of radiation or chemotherapy.

Authors:  Y Agatsuma; P Fitzpatrick; A Kaul; R Kaul; R Kohli; A V Paves; P L Ogra
Journal:  Infect Immun       Date:  1979-10       Impact factor: 3.441

2.  Stimulation of human lymphocytes by cytomegalovirions and dense bodies.

Authors:  I Sarov; A M Larsen; I Heron; H K Andersen
Journal:  Med Microbiol Immunol       Date:  1978-11-17       Impact factor: 3.402

3.  Cell-mediated immunity of cytomegalovirus infection in normal subjects and cardiac transplant patients.

Authors:  R B Pollard; K H Rand; A M Arvin; T C Merigan
Journal:  J Infect Dis       Date:  1978-05       Impact factor: 5.226

Review 4.  Cell-mediated immunity in cytomegalovirus infections--a review.

Authors:  G V Quinnan; F A Ennis
Journal:  Comp Immunol Microbiol Infect Dis       Date:  1980       Impact factor: 2.268

5.  Cytomegalovirus-directed lymphocyte reactivity in healthy adults tested by a CMV-induced lymphocyte transformation test.

Authors:  C H Ten Napel; T H The; J Bijker; G C De Gast; M M Langenhuysen
Journal:  Clin Exp Immunol       Date:  1977-07       Impact factor: 4.330

6.  Lymphocyte blastogenesis and interferon production in adult human leukocyte cultures stimulated with cytomegalovirus antigens.

Authors:  S E Starr; B Dalton; T Garrabrant; K Paucker; S A Plotkin
Journal:  Infect Immun       Date:  1980-10       Impact factor: 3.441

7.  Lymphocyte transformation and interferon production in human mononuclear cell microcultures for assay of cellular immunity to herpes simplex virus.

Authors:  S Haahr; L Rasmussen; T C Merigan
Journal:  Infect Immun       Date:  1976-07       Impact factor: 3.441

8.  Strain-specific local and systemic cell-mediated immune responses to cytomegalovirus in humans.

Authors:  K R Beutner; A Morag; R Deibel; B Morag; D Raiken; P L Ogra
Journal:  Infect Immun       Date:  1978-04       Impact factor: 3.441

9.  Comparison of in vitro lymphocyte proliferations induced by cytomegalovirus-infected human fibroblasts and cell-free cytomegalovirus.

Authors:  J Schirm; H W Roenhorst; T H The
Journal:  Infect Immun       Date:  1980-12       Impact factor: 3.441

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  1 in total

1.  Enhancive and suppressive effects of cytomegalovirus on human lymphocyte responses in vitro.

Authors:  B Wahren; P Ljungman; T Paulin; O Ringdén
Journal:  J Virol       Date:  1986-06       Impact factor: 5.103

  1 in total

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