Literature DB >> 628831

Rabies viruses increase in virulence when propagated in neuroblastoma cell culture.

H F Clark.   

Abstract

Several strains of attenuated rabies virus lacking the capacity to kill adult mice acquired a high lethal potential for mice after one to five serial passages in murine or human neuroblastoma cells. The virulence acquired after passage in neuroblastoma cells is a stable genetic trait retained during subsequent passage of viruses in nonneuroblastoma cell systems.

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Year:  1978        PMID: 628831     DOI: 10.1126/science.628831

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  10 in total

Review 1.  The genetics of vesiculoviruses.

Authors:  C R Pringle
Journal:  Arch Virol       Date:  1982       Impact factor: 2.574

2.  Host cell receptors for two strains of Sindbis virus.

Authors:  A L Smith; G H Tignor
Journal:  Arch Virol       Date:  1980       Impact factor: 2.574

3.  Neuroattenuated bunyavirus variant: derivation, characterization, and revertant clones.

Authors:  M J Endres; A Valsamakis; F Gonzalez-Scarano; N Nathanson
Journal:  J Virol       Date:  1990-05       Impact factor: 5.103

4.  Characterization of an antigenic determinant of the glycoprotein that correlates with pathogenicity of rabies virus.

Authors:  B Dietzschold; W H Wunner; T J Wiktor; A D Lopes; M Lafon; C L Smith; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1983-01       Impact factor: 11.205

5.  Virulence of tissue culture-propagated canine distemper virus.

Authors:  A E Metzler; R J Higgins; S Krakowka; A Koestner
Journal:  Infect Immun       Date:  1980-09       Impact factor: 3.441

6.  Mutants of rabies viruses in skunks: immune response and pathogenicity.

Authors:  N D Tolson; K M Charlton; R B Stewart; G A Casey; W A Webster; K MacKenzie; J B Campbell; K F Lawson
Journal:  Can J Vet Res       Date:  1990-01       Impact factor: 1.310

7.  Enteric inoculation with ERA rabies virus: evaluation of a candidate wildlife vaccine in laboratory rodents.

Authors:  K G Nicholson; S P Bauer
Journal:  Arch Virol       Date:  1981       Impact factor: 2.574

8.  Cross-protection of mice against a global spectrum of rabies virus variants.

Authors:  D L Lodmell; J S Smith; J J Esposito; L C Ewalt
Journal:  J Virol       Date:  1995-08       Impact factor: 5.103

9.  Rabies serogroup viruses in neuroblastoma cells: propagation, "autointerference," and apparently random back-mutation of attenuated viruses to the virulent state.

Authors:  H F Clark
Journal:  Infect Immun       Date:  1980-03       Impact factor: 3.441

10.  Comparative study of rabies virus persistence in human and hamster cell lines.

Authors:  O G Andzhaparidze; N N Bogomolova; Y S Boriskin; M S Bektemirova; I D Drynov
Journal:  J Virol       Date:  1981-01       Impact factor: 5.103

  10 in total

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