| Literature DB >> 628831 |
Abstract
Several strains of attenuated rabies virus lacking the capacity to kill adult mice acquired a high lethal potential for mice after one to five serial passages in murine or human neuroblastoma cells. The virulence acquired after passage in neuroblastoma cells is a stable genetic trait retained during subsequent passage of viruses in nonneuroblastoma cell systems.Entities:
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Year: 1978 PMID: 628831 DOI: 10.1126/science.628831
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728