Literature DB >> 6287560

Serum deoxyribonuclease I and clinical activity in systemic lupus erythematosus.

S Chitrabamrung, R L Rubin, E M Tan.   

Abstract

Serum deoxyribonuclease I (DNase I) activity in systemic lupus erythematosus (SLE) patients was shown to be lower than that of healthy laboratory personnel, rheumatoid arthritis, and scleroderma patients (P less than 0.001). The decrease in DNase I activity in SLE sera was not due to the effect of various autoantibodies or to heat labile DNase I inhibitor. A relationship between serum DNase I activity and active SLE was demonstrated. Patients with active lupus nephritis had the lowest levels of enzymatic activity.

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Year:  1981        PMID： 6287560     DOI： 10.1007/bf00541153

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN： 0172-8172            Impact factor:   2.631


  35 in total

1.  Nucleases and their inhibitors in the cellular components of human blood.

Authors:  S GUPTA; R M HERRIOTT
Journal:  Arch Biochem Biophys       Date:  1963-04       Impact factor: 4.013

2.  1958 Revision of diagnostic criteria for rheumatoid arthritis.

Authors:  M W ROPES; G A BENNETT; S COBB; R JACOX; R A JESSAR
Journal:  Bull Rheum Dis       Date:  1958-12

3.  The viscosimetric determination of desoxyribonuclease inhibition.

Authors:  H H HENSTELL; R I FREEDMAN
Journal:  Cancer Res       Date:  1952-05       Impact factor: 12.701

4.  B-lymphocyte alloantigens associated with systemic lupus erythematosus.

Authors:  J L Reinertsen; J H Klippel; A H Johnson; A D Steinberg; J L Decker; D L Mann
Journal:  N Engl J Med       Date:  1978-09-07       Impact factor: 91.245

5.  The relationship of desoxyribonuclease inhibitor levels in human sera to the occurrence of antinuclear antibodies.

Authors:  P G Frost; P J Lachmann
Journal:  Clin Exp Immunol       Date:  1968-06       Impact factor: 4.330

6.  Deoxyribonucleases in phytohemagglutinin-stimulated lymphocytes.

Authors:  E J Zöllner; M Reitz; R K Zahn; H Slor
Journal:  Exp Cell Res       Date:  1979-10-15       Impact factor: 3.905

7.  Immune function in systemic lupus erythematosus. Impairment of in vitro T-cell proliferation and in vivo antibody response to exogenous antigen.

Authors:  A B Gottlieb; R G Lahita; N Chiorazzi; H G Kunkel
Journal:  J Clin Invest       Date:  1979-05       Impact factor: 14.808

8.  Quantitation and characterization of plasma DNA in normals and patients with systemic lupus erythematosus.

Authors:  L Raptis; H A Menard
Journal:  J Clin Invest       Date:  1980-12       Impact factor: 14.808

9.  Immunoglobulin synthesis by peripheral blood cells in systemic lupus erythematosus.

Authors:  H E Jasin; M Ziff
Journal:  Arthritis Rheum       Date:  1975 May-Jun

10.  Lymphocyte response to virus antigens in systemic lupus erythematosus.

Authors:  R E Wolf; M Ziff
Journal:  Arthritis Rheum       Date:  1976 Nov-Dec
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  47 in total

Review 1.  Structural modification of DNA--a therapeutic option in SLE?

Authors:  Steffen Frese; Betty Diamond
Journal:  Nat Rev Rheumatol       Date:  2011-10-18       Impact factor: 20.543

Review 2.  Defects in the disposal of dying cells lead to autoimmunity.

Authors:  Udo S Gaipl; Sandra Franz; Reinhard E Voll; Ahmed Sheriff; Joachim R Kalden; Martin Herrmann
Journal:  Curr Rheumatol Rep       Date:  2004-12       Impact factor: 4.592

3.  Study of DNASE I gene polymorphisms in systemic lupus erythematosus susceptibility.

Authors:  Ana Bodaño; Antonio González; Eva Balada; Josep Ordi; Patricia Carreira; Juan J Gómez-Reino; Carmen Conde
Journal:  Ann Rheum Dis       Date:  2007-04       Impact factor: 19.103

4.  Acquired loss of renal nuclease activity is restricted to DNaseI and is an organ-selective feature in murine lupus nephritis.

Authors:  Natalya Seredkina; Ole P Rekvig
Journal:  Am J Pathol       Date:  2011-06-30       Impact factor: 4.307

5.  Defective degradation of bacterial DNA by phagocytes from patients with systemic and discoid lupus erythematosus.

Authors:  P J Roberts; D A Isenberg; A W Segal
Journal:  Clin Exp Immunol       Date:  1987-07       Impact factor: 4.330

6.  Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice.

Authors:  A Wilber; T P O'Connor; M L Lu; A Karimi; M C Schneider
Journal:  Clin Exp Immunol       Date:  2003-10       Impact factor: 4.330

7.  Identification of the functional alleles of the nonsynonymous single-nucleotide polymorphisms potentially implicated in systemic lupus erythematosus in the human deoxyribonuclease I gene.

Authors:  Kaori Kimura-Kataoka; Misuzu Ueki; Haruo Takeshita; Junko Fujihara; Reiko Iida; Yasuyuki Kawai; Toshihiro Yasuda
Journal:  DNA Cell Biol       Date:  2014-05-12       Impact factor: 3.311

8.  Circulating mitochondrial DNA and Toll-like receptor 9 are associated with vascular dysfunction in spontaneously hypertensive rats.

Authors:  Cameron G McCarthy; Camilla F Wenceslau; Styliani Goulopoulou; Safia Ogbi; Babak Baban; Jennifer C Sullivan; Takayuki Matsumoto; R Clinton Webb
Journal:  Cardiovasc Res       Date:  2015-04-24       Impact factor: 10.787

Review 9.  Treatment of lupus nephritis.

Authors:  Fayez F Hejaili; Louise M Moist; William F Clark
Journal:  Drugs       Date:  2003       Impact factor: 9.546

Review 10.  The role of dendritic cells in the pathogenesis of systemic lupus erythematosus.

Authors:  Justin H Fransen; Johan van der Vlag; Jurjen Ruben; Gosse J Adema; Jo H Berden; Luuk B Hilbrands
Journal:  Arthritis Res Ther       Date:  2010-04-26       Impact factor: 5.156
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