Literature DB >> 6287300

Comparative pharmacology of mianserin, its main metabolites and 6-azamianserin.

V J Nickolson, J H Wieringa, A M van Delft.   

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Year:  1982        PMID： 6287300     DOI： 10.1007/bf00491478

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


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  26 in total

1.  Presynaptic alpha-receptor subsensitivity after long-term antidepressant treatment.

Authors:  F T Crews; C B Smith
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2.  Presynaptic alpha-block and inhibition of noradrenaline and 5-hydroxytryptamine reuptake by a series of compounds related to mianserin.

Authors:  V J Nickolson; J H Wieringa
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3.  Functional evidence for subsensitivity of noradrenergic alpha 2 receptors after chronic desipramine treatment.

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4.  Tricyclic antidepressant drug interactions with histamine and alpha-adrenergic receptors.

Authors:  S H Snyder
Journal:  Pharmakopsychiatr Neuropsychopharmakol       Date:  1980-03

5.  Adrenergic and serotonergic receptor binding in rat brain after chronic desmethylimipramine treatment.

Authors:  D A Bergstrom; K J Kellar
Journal:  J Pharmacol Exp Ther       Date:  1979-05       Impact factor: 4.030

6.  Tricyclic antidepressant agents. I. Comparison of the inhibition of the uptake of 3-H-noradrenaline and 14-C-5-hydroxytryptamine in slices and crude synaptosome preparations of the midbrain-hypothalamus region of the rat brain.

Authors:  S B Ross; A L Renyi
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1975

7.  The tetracyclic antidepressant mianserin: evaluation of its blockade of presynaptic alpha-adrenoceptors in a self-stimulation model using clonidine.

Authors:  G E Hunt; D M Atrens; G F Johnson
Journal:  Eur J Pharmacol       Date:  1981-03-05       Impact factor: 4.432

8.  The metabolism of mianserin in women, rabbits, and rats: identification of the major urinary metabolites.

Authors:  G D de Jongh; H M van den Wildenberg; H Nieuwenhuyse; F van der Veen
Journal:  Drug Metab Dispos       Date:  1981 Jan-Feb       Impact factor: 3.922

9.  Inhibition of the neuronal uptake of 5-hydroxytryptamine and noradrenaline in rat brain by (Z)- and (E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridyl) allylamines and their secondary analogues.

Authors:  S B Ross; A L Renyi
Journal:  Neuropharmacology       Date:  1977-01       Impact factor: 5.250

10.  Detailed analysis of the effects of apomorphine and d-amphetamine on spontaneous locomotor behaviour of rats as measured in a TV-based, automated open-field system.

Authors:  V J Nickolson
Journal:  Eur J Pharmacol       Date:  1981-06-10       Impact factor: 4.432
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1.  Novel sigma (sigma) receptor agonists produce antidepressant-like effects in mice.

Authors:  Jiajia Wang; Aisha L Mack; Andrew Coop; Rae R Matsumoto
Journal:  Eur Neuropsychopharmacol       Date:  2007-03-21       Impact factor: 4.600

2.  Effect of the antidepressant Org 3770 on human sleep.

Authors:  G S Ruigt; B Kemp; C M Groenhout; H A Kamphuisen
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

3.  Antidepressant drugs with differing pharmacological actions decrease activity of locus coeruleus neurons.

Authors:  Charles H K West; James C Ritchie; Katherine A Boss-Williams; Jay M Weiss
Journal:  Int J Neuropsychopharmacol       Date:  2008-10-27       Impact factor: 5.176

4.  5-HT1C receptor antagonists have anxiolytic-like actions in the rat social interaction model.

Authors:  G A Kennett
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5.  [N-methyl-11C]Mirtazapine for positron emission tomography neuroimaging of antidepressant actions in humans.

Authors:  Katalin Marthi; Steen Jakobsen; Dirk Bender; Søren B Hansen; Stefan Bo Smith; Flemming Hermansen; Raben Rosenberg; Donald F Smith
Journal:  Psychopharmacology (Berl)       Date:  2004-07       Impact factor: 4.530

6.  Comparison of the effects of mianserin and its enantiomers and metabolites on a behavioral screen for antidepressant activity.

Authors:  T H Hand; G J Marek; L S Seiden
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

7.  Differential blockade by (-)mianserin of the alpha 2-adrenoceptors mediating inhibition of noradrenaline and serotonin release from rat brain synaptosomes.

Authors:  M Raiteri; G Maura; A Gemignani; A Pittaluga
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1983-03       Impact factor: 3.000

8.  Pharmaco-EEG study of 6-azamianserin (ORG 3770): dissociation of EEG and pharmacologic predictors of antidepressant activity.

Authors:  M Fink; P Irwin
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

9.  Evidence that mCPP may have behavioural effects mediated by central 5-HT1C receptors.

Authors:  G A Kennett; G Curzon
Journal:  Br J Pharmacol       Date:  1988-05       Impact factor: 8.739

Review 10.  Metabolic N-Dealkylation and N-Oxidation as Elucidators of the Role of Alkylamino Moieties in Drugs Acting at Various Receptors.

Authors:  Babiker M Eh-Haj
Journal:  Molecules       Date:  2021-03-29       Impact factor: 4.411
  10 in total

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