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Literature DB >> 6287040

Effects of fowlpox virus infection on lipid metabolism in cultured chicken embryo cells.

Abstract

Lipid biosynthesis was measured in cultured chicken embryo cells after infection with fowlpox virus. Between 24 and 72 h postinfection, fowlpox virus-infected cells incorporated less [14C]acetate and 3H2O into fatty acids and sterols than did mock-infected cells, demonstrating a virus-dependent inhibition of general lipid metabolism. Two specific effects of fowlpox virus infection were an accumulation of C-4 alkylated sterol intermediates and inhibition of monounsaturated fatty acid biosynthesis.

Entities: Chemical Disease Species

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Year: 1982 PMID： 6287040 PMCID： PMC256179

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

24 in total

Effects of fowlpox virus infection on lipid metabolism in cultured chicken embryo cells.

1. The effect of poliomyelitis virus type I (Mahoney strain) on the phosphorus metabolism of the HeLa cell.

2. Cellular fatty acids during fowlpox virus infection of three different host systems.

3. An alteration in the kinetic properties of a cholesterogenic enzyme in fowlpox virus infection.

4. Virus-induced cholesterol crystals.

5. The occurrence of squalene in kipid of fowlpox virus.

6. Growth cycle of fowlpox virus and change in plaque morphology and cytopathology by contaminating mycoplasma.

7. Odd-and even-numbered fatty acids. Their contrasting behavior in normal and fowlpox virus-infected epithelium.

8. The correlation of fatty acid content of infected cells and virions with Newcastle disease virus (NDV) virulence.

9. Phospholipid synthesis in human embryo fibroblasts infected with herpes simplex virus type 2.

10. Total enzymic synthesis of cholesterol from lanosterol. Cytochrome b5-dependence of 4-methyl sterol oxidase.

1. Hepatic lipid abnormalities in a chemical/viral mouse model for Reye's syndrome.