Literature DB >> 6286044

Rapid appearance of intraventricularly administered neuropeptides in the peripheral circulation.

E Passaro, H Debas, W Oldendorf, T Yamada.   

Abstract

125I-Labeled cholecystokinin octapeptide ([125I]CCK-OP) diffuses rapidly by a non-carrier-mediated mechanism into the peripheral blood following injection into the lateral ventricle of a rabbit. In contrast, no [125I]CCK-OP was observed in the CSF following intravenous injection. This unidirectional free transport mechanism from CSF to blood may apply to other neuropeptides as well.

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Year:  1982        PMID： 6286044

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  16 in total

1.  Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways: implications for leptin as a regulator of short term satiety.

Authors:  Andrea Heldsinger; Gintautas Grabauskas; Il Song; Chung Owyang
Journal:  J Biol Chem       Date:  2011-01-26       Impact factor: 5.157

2.  Drug transport into the central nervous system: using newer findings about the blood-brain barriers.

Authors:  William A Banks
Journal:  Drug Deliv Transl Res       Date:  2012-06       Impact factor: 4.617

3.  Effect of peripherally and centrally administered calcitonin on gallbladder emptying in dogs.

Authors:  K Jonderko; L Buéno
Journal:  J Gastroenterol       Date:  1997-06       Impact factor: 7.527

Review 4.  Cerebrovascular permeability to peptides: manipulations of transport systems at the blood-brain barrier.

Authors:  B V Zlokovic
Journal:  Pharm Res       Date:  1995-10       Impact factor: 4.200

5.  Bombesin-induced anorexia requires central bombesin receptor activation: independence from interaction with central catecholaminergic systems.

Authors:  F Motamedi; A Rashidy-Pour; M R Zarrindast; M Badavi
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

6.  PEGylated cholecystokinin is more potent in inducing anorexia than conditioned taste aversion in rats.

Authors:  I Verbaeys; F León-Tamariz; H Pottel; E Decuypere; Q Swennen; M Cokelaere
Journal:  Br J Pharmacol       Date:  2008-06-23       Impact factor: 8.739

7.  2-Naphthalenesulphanyl-L-aspartyl-2-(phenethyl) amide (2-NAP) and food intake in rats: evidence that endogenous peripheral CCK does not play a major role as a satiety factor.

Authors:  I S Ebenezer; B A Baldwin
Journal:  Br J Pharmacol       Date:  1995-11       Impact factor: 8.739

8.  Dose ranging study of the effects of cholecystokinin in healthy volunteers.

Authors:  J Bradwejn; D Koszycki; M Bourin
Journal:  J Psychiatry Neurosci       Date:  1991-07       Impact factor: 6.186

9.  PEGylated cholecystokinin prolongs satiation in rats: dose dependency and receptor involvement.

Authors:  I Verbaeys; F León-Tamariz; J Buyse; M De Cuyper; H Pottel; M Van Boven; M Cokelaere
Journal:  Br J Pharmacol       Date:  2007-07-09       Impact factor: 8.739

10.  Transport and distribution of homocarnosine after intracerebroventricular and intravenous injection in the rat.

Authors:  O Ziesler; K Hole; I Haugan; A L Børresen; L R Gjessing; O Sjaastad
Journal:  Neurochem Res       Date:  1984-05       Impact factor: 3.996
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