Literature DB >> 6286008

Microinjection of cyclic nucleotides provides evidence for a diffusional mechanism of intraneuronal control.

E A Liberman, S V Minina, N E Shklovsky-Kordy, M Conrad.   

Abstract

Cyclic 3',5'-AMP and cyclic 3',5'-GMP injected into large neurons of the snail Helix lucorum altered neuron activity. The effect of cAMP is usually depolarizing and that of cGMP hyperpolarizing. The results are specific for 3',5'-cyclic nucleotides. The experiments support the hypothesis that reaction-diffusion processes involving cyclic nucleotides form the basis of an intraneuronal system of information processing.

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Year:  1982        PMID: 6286008     DOI: 10.1016/0303-2647(82)90026-0

Source DB:  PubMed          Journal:  Biosystems        ISSN: 0303-2647            Impact factor:   1.973


  2 in total

1.  Computational modeling of evolutionary learning processes in the brain.

Authors:  R R Kampfner; M Conrad
Journal:  Bull Math Biol       Date:  1983       Impact factor: 1.758

2.  The enzymatic neuron as a reaction-diffusion network of cyclic nucleotides.

Authors:  K G Kirby; M Conrad
Journal:  Bull Math Biol       Date:  1984       Impact factor: 1.758

  2 in total

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