Literature DB >> 6285706

Effect of acyclovir, bromovinyldeoxyuridine, vidarabine, and L-lysine on latent ganglionic herpes simplex virus in vitro.

N H Park, D Pavan-Langston, E Declercq.   

Abstract

Vidarabine and L-lysine did not prevent the in vitro reactivation of latent herpes simplex virus or block the further multiplication of reactivated latent virus. Acyclovir and bromovinyldeoxyuridine both blocked the reaction and the multiplication of reactivated latent virus, and transiently suppressed but did not eliminate latent virus from the sensory ganglia.

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Year:  1982        PMID: 6285706     DOI: 10.1016/0002-9343(82)90081-x

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  8 in total

Review 1.  Herpes simplex virus ocular infections: current concepts of acute, latent and reactivated disease.

Authors:  D Pavan-Langston
Journal:  Trans Am Ophthalmol Soc       Date:  1990

2.  Effects of 2,2'-O-cyclocytidine and acyclovir on latent herpes simplex virus in trigeminal ganglia of mice.

Authors:  W G Liu; Z J Chen; J Z Song; Z X Ma
Journal:  Antimicrob Agents Chemother       Date:  1986-02       Impact factor: 5.191

3.  Effect of discontinuous acyclovir treatment on in vitro reactivation of herpes simplex virus from latently infected trigeminal ganglia.

Authors:  R J Klein; A E Friedman-Kien; E DeStefano
Journal:  Antimicrob Agents Chemother       Date:  1983-07       Impact factor: 5.191

4.  Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on the acute local phase of herpes simplex virus-induced skin infections in mice and the establishment of latency.

Authors:  R J Klein; A E Friedman-Kien
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

Review 5.  Acyclovir. A review of its pharmacodynamic properties and therapeutic efficacy.

Authors:  D M Richards; A A Carmine; R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1983-11       Impact factor: 9.546

Review 6.  Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  J J O'Brien; D M Campoli-Richards
Journal:  Drugs       Date:  1989-03       Impact factor: 9.546

7.  Analysis of Herpes Simplex Virus Reactivation in Explant Reveals a Method-Dependent Difference in Measured Timing of Reactivation.

Authors:  Jessica R Doll; Nancy M Sawtell
Journal:  J Virol       Date:  2017-07-27       Impact factor: 5.103

Review 8.  Lysine supplementation is not effective for the prevention or treatment of feline herpesvirus 1 infection in cats: a systematic review.

Authors:  Sebastiaan Bol; Evelien M Bunnik
Journal:  BMC Vet Res       Date:  2015-11-16       Impact factor: 2.741

  8 in total

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