Literature DB >> 6284303

Attenuation by chronic imipramine treatment of [3H]clonidine binding to cortical membranes and of clonidine-induced hypothermia: the influence of central chemosympathectomy.

A Pilc, J Vetulani.   

Abstract

Central chemosympathectomy with intraventricular injection of 250 microgram of 6-hydroxydopamine, resulting in depression of cerebral noradrenaline level by 75% led to an increase in specific binding of [3H]clonidine to cerebral cortical membranes, but did not affect the hypothermic response to clonidine. Chronic imipramine treatment depressed [3H]clonidine binding and attenuated clonidine-induced hypothermia similarly in non-chemosympathectomized and chemosympathectomized rats.

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Year:  1982        PMID： 6284303     DOI： 10.1016/0006-8993(82)90131-7

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  9 in total

1.  Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS.

Authors:  J A Gray; G M Goodwin; D J Heal; A R Green
Journal:  Br J Pharmacol       Date:  1987-12       Impact factor: 8.739

Review 2.  Effects of long-term administration of antidepressants and neuroleptics on receptors in the central nervous system.

Authors:  G B Baker; A J Greenshaw
Journal:  Cell Mol Neurobiol       Date:  1989-03       Impact factor: 5.046

3.  The responsiveness of cerebral cortical adrenergic receptors after chronic administration of atypical antidepressant mianserin.

Authors:  I Nalepa; J Vetulani
Journal:  J Psychiatry Neurosci       Date:  1994-03       Impact factor: 6.186

4.  Activation and desensitization of presynaptic alpha 2-adrenoceptors after inhibition of neuronal uptake by antidepressant drugs in the rat vas deferens.

Authors:  J A García-Sevilla; J K Zubieta
Journal:  Br J Pharmacol       Date:  1986-12       Impact factor: 8.739

5.  Role of cortical alpha-2 adrenoceptors in alcohol withdrawal-induced depression and tricyclic antidepressants.

Authors:  Bruk Getachew; Sheketha R Hauser; Antonei B Csoka; Robert E Taylor; Yousef Tizabi
Journal:  Drug Alcohol Depend       Date:  2017-04-04       Impact factor: 4.492

6.  Adaptive and differential changes on beta- and alpha 2-adrenoreceptors mediated hyperthermia after chronic treatment with antidepressant drugs in the rat kept at high ambient temperature.

Authors:  E Mogilnicka; V Klimek; G Nowak; A Czyrak
Journal:  J Neural Transm       Date:  1985       Impact factor: 3.575

7.  Chronic treatment with imipramine: further functional evidence for the enhanced noradrenergic transmission in flexor reflex activity.

Authors:  J Maj; Z Górka; M Melzacka; A Rawłów; A Pilc
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1983-05       Impact factor: 3.000

8.  Biochemical and pharmacological effects of fluperlapine on noradrenaline and acetylcholine systems in some rodent, bovine and crustacean preparations.

Authors:  C Rüdeberg; S Urwyler; C Schulthess; P L Herrling
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-04       Impact factor: 3.000

9.  Alpha-2 adrenergic-induced changes in rectal temperature in adult and 13-day old rats following acute and repeated desipramine administration.

Authors:  Jean D Deupree; William J Burke; David B Bylund
Journal:  BMC Pharmacol       Date:  2008-10-02
  9 in total

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