Literature DB >> 6284195

The influence of cyclic nucleotides on DNA synthesis in skin.

S A Carney.   

Abstract

Total saline-soluble protein, total DNA, and 3H-thymidine labelling of DNA were measured in cultured guinea-pig skin during a 3-day incubation period. An early rise in total soluble protein and a fall in total DNA indicated loss of the cells damaged in cutting the skin samples. Samples incubated with dibutyryl cyclic adenosine monophosphate (db cAMP) showed an early stimulation of DNA synthesis. Cyclic guanosine monophosphate (cGMP) stimulation of DNA synthesis showed a peak after 48 h incubation, probably reflecting a slower rate of entry of the compound into the epidermal cells.

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Year:  1982        PMID： 6284195      PMCID： PMC2040637     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  9 in total

1.  Effect of antibiotics on tissue cultures of human skin.

Authors:  C N D CRUICKSHANK; E J L LOWBURY
Journal:  Br Med J       Date:  1952-11-15

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

Review 3.  William Montagna Lecture. Cyclic nucleotides and epidermal cell proliferation.

Authors:  K M Halprin
Journal:  J Invest Dermatol       Date:  1976-06       Impact factor: 8.551

4.  Interrelation of epithelial glycogen, cell proliferation and cellular migration with cyclic adenosine monophosphate in epithelial wound healing.

Authors:  J P Williams
Journal:  Cell Differ       Date:  1972-12

5.  Dibutyryl cyclic AMP inhibition of epidermal cell division.

Authors:  J J Voorhees; E A Duell; W H Kelsey
Journal:  Arch Dermatol       Date:  1972-03

6.  The initiation of epidermal wound healing in cuts and burns.

Authors:  E Hell; J C Lawrence
Journal:  Br J Exp Pathol       Date:  1979-04

7.  Grafting of burns with cultured epithelium prepared from autologous epidermal cells.

Authors: 
Journal:  Lancet       Date:  1981-01-10       Impact factor: 79.321

8.  The effects of epidermal growth factor on the cyclic nucleotide system in pig epidermis.

Authors:  T Aoyagi; K Adachi; K M Halprin; V Levine
Journal:  J Invest Dermatol       Date:  1980-04       Impact factor: 8.551

9.  Cyclic AMP in relation to proliferation of the epidermal cell: a new view.

Authors:  H Green
Journal:  Cell       Date:  1978-11       Impact factor: 41.582
  9 in total

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