Literature DB >> 6284194

Serum inhibitory effect on myeloperoxidase in human cancer.

B Senelar, R Michel, J Tournamille, H Vannereau, M J Escola, J Taib, A Craste de Paulet.   

Abstract

The myeloperoxidase level is strongly depressed in leucocytes from cancer patients (-59%). Moreover sera of the same subjects induce a significant decrease in the myeloperoxidase activity of healthy subjects' leucocytes (-43%). We have found no convincing evidence of any correlation between the level of the inhibitory effect of sera and the tumour type. The fact that sera from cancer patients interfere with neutrophil responses in this way does not exclude the possibility that abnormal cellular functions were also operative.

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Year:  1982        PMID: 6284194      PMCID: PMC2040634     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


  32 in total

1.  Characterization of serum inhibitors of neutrophil chemotaxis associated with anergy.

Authors:  D E Van Epps; D L Palmer; R C Williams
Journal:  J Immunol       Date:  1974-07       Impact factor: 5.422

2.  Abnormal monocyte chemotactic response in cancer patients.

Authors:  D A Boetcher; E J Leonard
Journal:  J Natl Cancer Inst       Date:  1974-04       Impact factor: 13.506

3.  Defective regulation of inflammatory mediators in Hodgkin's disease. Supernormal levels of chemotactic-factor inactivator.

Authors:  P A Ward; J L Berenberg
Journal:  N Engl J Med       Date:  1974-01-10       Impact factor: 91.245

4.  Studies on the role of polymorphonuclear leukocytes in neoplastic disease with the chick embryo and Walker carcinosarcoma 256 in vivo and in vitro.

Authors:  J J Godleski; R E Lee; J Leighton
Journal:  Cancer Res       Date:  1970-07       Impact factor: 12.701

5.  A factor in maternal plasma during pregnancy that suppresses the reactivity of mixed leukocyte cultures.

Authors:  S Kasakura
Journal:  J Immunol       Date:  1971-11       Impact factor: 5.422

6.  Impaired immunologic reactivity and recurrence following cancer surgery.

Authors:  F R Eilber; D L Morton
Journal:  Cancer       Date:  1970-02       Impact factor: 6.860

7.  Skin reactivity in patients with cancer. Impaired delayed hypersensitivity or faulty inflammatory response?

Authors:  M W Johnson; H I Maibach; S E Salmon
Journal:  N Engl J Med       Date:  1971-06-03       Impact factor: 91.245

8.  Two distinct chemotactic factor inactivators in human serum.

Authors:  G Till; P A Ward
Journal:  J Immunol       Date:  1975-02       Impact factor: 5.422

9.  Antiinflammatory effects of murine malignant cells.

Authors:  R M Fauve; B Hevin; H Jacob; J A Gaillard; F Jacob
Journal:  Proc Natl Acad Sci U S A       Date:  1974-10       Impact factor: 11.205

10.  Neutrophil-mediated tumor cell cytotoxicity: role of the peroxidase system.

Authors:  R A Clark; S J Klebanoff
Journal:  J Exp Med       Date:  1975-06-01       Impact factor: 14.307

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