| Literature DB >> 6282715 |
Abstract
The Lactobacillus casei gene for dihydrofolate reductase has been cloned in Escherichia coli using the multicopy vector pBR322. A restriction map of the cloned DNA has been prepared. The cloned DNA directs the synthesis of L. casei dihydrofolate reductase in E. coli and confers trimethoprim and methotrexate resistance.Entities:
Mesh:
Substances:
Year: 1982 PMID: 6282715 DOI: 10.1016/0378-1119(82)90077-4
Source DB: PubMed Journal: Gene ISSN: 0378-1119 Impact factor: 3.688