| Literature DB >> 6282665 |
Y Shibata, H Ohzeki, M Sato, Y Suzuki, H Takiguchi.
Abstract
1. The Na+-K+-ATPase activity in the synaptic plasma membrane of rat brain was inhibited by PGA2 in vitro. 2. PGA2 concentration required for 50% inhibition was 8.91 x 10(-5) M. 3. Inhibition mode of PGA2 for both ATP and Mg2+ was uncompetitive type. 4. PGA2 was competitive and noncompetitive with Na+ and K+, respectively. 5. The Ki values for PGA2 inhibition for ATP. Na+, K+ and Mg2+ were 6.0 x 10(-5), 2.7 x 10(-5), 10.8 x 10(-5) and 0.6 x 10(-5) M, respectively.Entities:
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Year: 1982 PMID： 6282665 DOI： 10.1016/0020-711x(82)90016-7
Source DB: PubMed Journal: Int J Biochem ISSN： 0020-711X