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Literature DB >> 6281189

In vitro amoebicidal activity of immune cells.

Abstract

The amoebicidal activity of peripheral blood lymphocytes and spleen and peritoneal cells from hamsters vaccinated against or protected from hepatic amoebiasis and from those with hepatic amoebiasis was investigated. Peripheral blood lymphocytes and peritoneal and spleen cells from vaccinated or protected animals can kill trophozoites of Entamoeba histolytica in vitro. In contrast, spleen cells from infected hamsters showed no significant cytotoxic effect on the parasite. These data suggest that cellular immunity plays an important role in host defense against hepatic amoebiasis.

Entities: Disease Species

Mesh：

Year: 1982 PMID： 6281189 PMCID： PMC351210 DOI： 10.1128/iai.36.1.243-246.1982

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

21 in total

1. [Cellular hypersensitivity in amebiasis. I. Reactions in hamsters inoculated with E. histolytica].

Authors: L Ortiz-Ortiz; C Garmilla; M Tanimoto-Weki; G Zamacona-Ravelo
Journal: Arch Invest Med (Mex) Date: 1973

2. Blast transformation of lymphocytes in amebiasis.

Authors: T Savanat; P Viriyanond; N Nimitmongkol
Journal: Am J Trop Med Hyg Date: 1973-11 Impact factor: 2.345

3. Histopathology of tumor regression after intralesional injection of Mycobacterium bovis. I. Tumor growth and metastasis.

Authors: M G Hanna; B Zbar; H J Rapp
Journal: J Natl Cancer Inst Date: 1972-05 Impact factor: 13.506

4. Tumor cytotoxicity in vitro by macrophages from mice infected with mycobacterium bovis strain BCG.

Authors: R P Cleveland; M S Meltzer; B Zbar
Journal: J Natl Cancer Inst Date: 1974-06 Impact factor: 13.506

5. A role for activated macrophages in resistance to infection with Toxoplasma.

Authors: J S Remington; J L Krahenbuhl; J W Mendenhall
Journal: Infect Immun Date: 1972-11 Impact factor: 3.441

6. Trypanosoma lewisi: in vitro behavior of rat spleen cells.

Authors: C L Greenblatt; E Tyroler
Journal: Exp Parasitol Date: 1971-12 Impact factor: 2.011

7. In vitro induction of nonspecific resistance in macrophages by specifically sensitized lymphocytes.

Authors: J L Krahenbuhl; J S Remington
Journal: Infect Immun Date: 1971-10 Impact factor: 3.441

8. Correlation of increased metabolic activity, resistance to infection, enhanced phagocytosis, and inhibition of bacterial growth by macrophages from Listeria- and BCG-infected mice.

Authors: K R Ratzan; D M Musher; G T Keusch; L Weinstein
Journal: Infect Immun Date: 1972-04 Impact factor: 3.441

9. Techniques of axenic cultivation of Entamoeba histolytica Schaudinn, 1903 and E. histolytica-like amebae.

Authors: L S Diamond
Journal: J Parasitol Date: 1968-10 Impact factor: 1.276

10. An examination of the cytotoxic effects of silica on macrophages.

Authors: A C Allison; J S Harington; M Birbeck
Journal: J Exp Med Date: 1966-08-01 Impact factor: 14.307

9 in total

1. In vitro and in vivo studies of macrophage functions in amebiasis.

Authors: M Denis; K Chadee
Journal: Infect Immun Date: 1988-12 Impact factor: 3.441

2. Alterations of humoral, cell mediated and antibody dependent cell mediated cytotoxic responses during the course of amoebic infection in guinea pigs.

Authors: V K Vinayak; A Saxena; A K Malik
Journal: Gut Date: 1987-10 Impact factor: 23.059

Review 3. Cytopathogenicity of Entamoeba histolytica: the role of amebic adherence and contact-dependent cytolysis in pathogenesis.

Authors: W A Petri; J I Ravdin
Journal: Eur J Epidemiol Date: 1987-06 Impact factor: 8.082