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Literature DB >> 6278417

A 3' co-terminus of two early herpes simplex virus type 1 mRNAs.

Abstract

A 3' co-terminus of two early herpes simplex virus type 1 mRNAs has been identified using the nuclease -S1 mapping procedure with cloned virus DNA probes. These mRNAs (5.0 kb and 1.2 kb), located within the genome region 0.56-0.60, are unspliced and are transcribed rightwards on the prototype genome orientation. The position of their 3' ends has been located on the virus DNA sequence and lies downstream from the polyadenylation signal 5'-AATAAA-3'. This hexanucleotide sequence also was present in the complementary DNA strand and was shown to be the polyadenylation signal for a leftwards-transcribed late mRNA. The abundance within the cytoplasm of the 5.0 kb and 1.2 kb mRNAs was investigated. Results indicated that these mRNAs were regulated in concert. It is suggested that sequences at the 3' co-terminus may be involved in their regulation.

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Year: 1982 PMID： 6278417 PMCID： PMC326153 DOI： 10.1093/nar/10.2.501

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

23 in total

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Authors: J B Clements; J McLauchlan; D J McGeoch
Journal: Nucleic Acids Res Date: 1979-09-11 Impact factor: 16.971

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Authors: J B Clements; R J Watson; N M Wilkie
Journal: Cell Date: 1977-09 Impact factor: 41.582

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Journal: J Virol Date: 1976-10 Impact factor: 5.103

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Journal: Science Date: 1978-05-05 Impact factor: 47.728

5. Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors: A J Berk; P A Sharp
Journal: Cell Date: 1977-11 Impact factor: 41.582

6. Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates.

Authors: R F Weaver; C Weissmann
Journal: Nucleic Acids Res Date: 1979-11-10 Impact factor: 16.971

7. 3' non-coding region sequences in eukaryotic messenger RNA.

Authors: N J Proudfoot; G G Brownlee
Journal: Nature Date: 1976-09-16 Impact factor: 49.962

8. The ovalbumin gene-sequence of putative control regions.

Authors: C Benoist; K O'Hare; R Breathnach; P Chambon
Journal: Nucleic Acids Res Date: 1980-01-11 Impact factor: 16.971

9. Structure and genomic organization of the mouse dihydrofolate reductase gene.

Authors: J H Nunberg; R J Kaufman; A C Chang; S N Cohen; R T Schimke
Journal: Cell Date: 1980-02 Impact factor: 41.582

10. Sequence of chicken ovalbumin mRNA.

Authors: L McReynolds; B W O'Malley; A D Nisbet; J E Fothergill; D Givol; S Fields; M Robertson; G G Brownlee
Journal: Nature Date: 1978-06-29 Impact factor: 49.962

14 in total

1. Vaccinia virus-encoded ribonucleotide reductase: sequence conservation of the gene for the small subunit and its amplification in hydroxyurea-resistant mutants.

Authors: M Slabaugh; N Roseman; R Davis; C Mathews
Journal: J Virol Date: 1988-02 Impact factor: 5.103

2. Herpes simplex virus specifies two subunits of ribonucleotide reductase encoded by 3'-coterminal transcripts.

Authors: M A Swain; D A Galloway
Journal: J Virol Date: 1986-03 Impact factor: 5.103

3. Regulation of cytomegalovirus late gene expression: gamma genes are controlled by posttranscriptional events.

Authors: A P Geballe; F S Leach; E S Mocarski
Journal: J Virol Date: 1986-03 Impact factor: 5.103

4. Expression of a human cytomegalovirus late gene is posttranscriptionally regulated by a 3'-end-processing event occurring exclusively late after infection.

Authors: W F Goins; M F Stinski
Journal: Mol Cell Biol Date: 1986-12 Impact factor: 4.272

5. Organization and expression of the immediate early genes of human cytomegalovirus.

Authors: M F Stinski; D R Thomsen; R M Stenberg; L C Goldstein
Journal: J Virol Date: 1983-04 Impact factor: 5.103

6. Detailed structural analysis of two spliced HSV-1 immediate-early mRNAs.

Authors: F J Rixon; J B Clements
Journal: Nucleic Acids Res Date: 1982-04-10 Impact factor: 16.971

7. RNAs transcribed from a 3.6-kilobase SmaI fragment of the short unique region of the herpes simplex virus type 1 genome.

Authors: K Ikura; J L Betz; J R Sadler; L I Pizer
Journal: J Virol Date: 1983-11 Impact factor: 5.103

8. Structural analysis of the major immediate early gene of human cytomegalovirus.

Authors: R M Stenberg; D R Thomsen; M F Stinski
Journal: J Virol Date: 1984-01 Impact factor: 5.103

9. The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini.

Authors: J McLauchlan; D Gaffney; J L Whitton; J B Clements
Journal: Nucleic Acids Res Date: 1985-02-25 Impact factor: 16.971

10. Characterization of the herpes simplex virus type 1 glycoprotein D mRNA and expression of this protein in Xenopus oocytes.

Authors: R J Watson; A M Colberg-Poley; C J Marcus-Sekura; B J Carter; L W Enquist
Journal: Nucleic Acids Res Date: 1983-03-11 Impact factor: 16.971