Literature DB >> 6277675

Sex and strain differences in benzodiazepine receptor binding in Roman rat strains.

R A Shephard, E B Nielsen, P L Broadhurst.   

Abstract

Specific [3H]flunitrazepam binding was determined for five brain regions in both sexes of the three Roman rat strains. Small strain differences and a large Sex-Region interaction were detected, benzodiazepine receptor binding being significantly higher in females in the two cortical areas and the cerebellum, but significantly lower in the striatum and hippocampus. These findings are discussed in the context of sex and strain differences in behavior and benzodiazepine sensitivity.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6277675     DOI： 10.1016/0014-2999(82)90137-6

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  8 in total

1.  Evidence of strain differences in GABA-benzodiazepine coupling.

Authors:  L Wilks; S E File; I L Martin
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

2.  Anxiolytic actions of chlordiazepoxide determine its effects on hyponeophagia in rats.

Authors:  R A shephard; L B Estall
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

3.  Autoradiographic analysis of GABAA receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats.

Authors:  Stephanie M Miller; Joseph S Lonstein
Journal:  Brain Res Bull       Date:  2011-06-01       Impact factor: 4.077

4.  Cerebral tryptophan hydroxylase activity, and 5-HT1A receptor, 5-HT2A receptor, and 5-HT transporter binding in grouped and isolated Roman RHA and RLA rats: relationships with behaviours in two models of anxiety.

Authors:  A Kulikov; N Castanon; P Mormède; F Chaouloff
Journal:  Psychopharmacology (Berl)       Date:  1995-10       Impact factor: 4.530

5.  The genetic architecture of hyponeophagia and the action of diazepam in rats.

Authors:  R A Shephard; J K Hewitt; P L Broadhurst
Journal:  Behav Genet       Date:  1985-05       Impact factor: 2.805

6.  Hyponeophagia and arousal in rats: effects of diazepam, 5-methoxy-N,N-dimethyltryptamine, d-amphetamine and food deprivation.

Authors:  R A Shephard; P L Broadhurst
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

7.  Estradiol and testosterone modulate the anesthetic action of the GABA-A agonist THIP, but not of the neurosteroid 3alpha,5beta-pregnanolone in the rat.

Authors:  Oscar González-Flores; Norma Sánchez; Marcos García-Juárez; Francisco Javier Lima-Hernández; Gabriela González-Mariscal; Carlos Beyer
Journal:  Psychopharmacology (Berl)       Date:  2003-12-17       Impact factor: 4.530

Review 8.  Genetic and environmental influences on behavioral and neurochemical aspects of emotionality in rats.

Authors:  C Gentsch; M Lichtsteiner; H Feer
Journal:  Experientia       Date:  1988-06-15
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.