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Literature DB >> 6276699

A new type of IS1-mediated deletion.

Abstract

Genetical tests and DNA sequence analysis revealed that the mechanism of formation of IS1-induced type I and type II deletions differs. IS1-mediated type II deletions occur at the termini of the integrated element and do not remove the element. This process is independent of the cellular recA system and does not involve DNA sequence homology. Conversely, the formation of IS1-induced type I deletions differs substantially. They require recA gene product, small DNA sequence duplications and a topological arrangement of the DNA molecule to allow alignment of duplications.

Entities: Gene

Mesh：

Substances：

Year: 1981 PMID： 6276699 DOI： 10.1007/bf00272921

Source DB: PubMed Journal: Mol Gen Genet ISSN： 0026-8925

14 in total

1. IS1 is involved in deletion formation in the gal region of E. coli K12.

Authors: H J Reif; H Saedler
Journal: Mol Gen Genet Date: 1975

2. Development of a system useful for studying the formation of unstable alleles of IS2.

Authors: P A Peterson; D Ghosal; H Sommer; H Saedler
Journal: Mol Gen Genet Date: 1979-05-23

3. Nucleotide sequence of the transposable DNA-element IS2.

Authors: D Ghosal; H Sommer; H Saedler
Journal: Nucleic Acids Res Date: 1979-03 Impact factor: 16.971

4. Genetic studies of the lac repressor. VII. On the molecular nature of spontaneous hotspots in the lacI gene of Escherichia coli.

Authors: P J Farabaugh; U Schmeissner; M Hofer; J H Miller
Journal: J Mol Biol Date: 1978-12-25 Impact factor: 5.469

5. Transformation of Salmonella typhimurium by plasmid deoxyribonucleic acid.

Authors: E M Lederberg; S N Cohen
Journal: J Bacteriol Date: 1974-09 Impact factor: 3.490

6. Insertion mutations in the control region of the galactose operon of E. coli. II. Physical characterization of the mutations.

Authors: H J Hirsch; H Saedler; P Starlinger
Journal: Mol Gen Genet Date: 1972

6. Transposon-induced alterations in the promoter region affect transcription of the chalcone synthase gene of Antirrhinum majus.

Authors: H Sommer; U Bonas; H Saedler
Journal: Mol Gen Genet Date: 1988-01

A new type of IS1-mediated deletion.

1. IS1 is involved in deletion formation in the gal region of E. coli K12.

2. Development of a system useful for studying the formation of unstable alleles of IS2.

3. Nucleotide sequence of the transposable DNA-element IS2.

4. Genetic studies of the lac repressor. VII. On the molecular nature of spontaneous hotspots in the lacI gene of Escherichia coli.

5. Transformation of Salmonella typhimurium by plasmid deoxyribonucleic acid.

6. Insertion mutations in the control region of the galactose operon of E. coli. II. Physical characterization of the mutations.

7. Integration of IS3 into IS2 generates a short sequence duplication.

8. IS1-mediated DNA rearrangements.

9. Three Tn10-associated excision events: relationship to transposition and role of direct and inverted repeats.

10. Nucleotide sequence of the operator-promoter region of the galactose operon of Escherichia coli.

1. Mechanisms of deletion formation in Escherichia coli plasmids. II. Deletions mediated by short direct repeats.

2. Genetic evidence of mutator-induced deletions in the short arm of chromosome 9 of maize.

3. A transcriptional terminator sequence in the prokaryotic transposable element IS1.

4. Atypical deletions generated by mutated IS102 elements.

5. Second-element turn-on of gene expression in an IS1 insertion mutant.

6. Transposon-induced alterations in the promoter region affect transcription of the chalcone synthase gene of Antirrhinum majus.

7. Nucleotide sequence analysis of in vivo recombinants between bacteriophage lambda DNA and pBR322.

8. Recombination between short direct repeats in a recA host.

9. Bidirectional deletions associated with IS4.

10. Recombination between short direct repeats in Streptomyces lavendulae plasmid DNA.