Literature DB >> 6276220

3H-Diazepam binding sites in Roman high- and low-avoidance rats.

C Gentsch, M Lichtsteiner, H Feer.   

Abstract

The binding of 3H-diazepam to membrane benzodiazepine receptors was examined in 2 psychogenetically selected lines of rats, which differ according to the selection criterion in avoidance behaviour (RHA/Verh greater than RLA/Verh) and, in addition, in emotionality (RHA/Verh less than RLA/Verh). RHA/Verh rats tended to show higher specific diazepam binding in all CNS-subregions when compared with RLA/Verh animals. Significant differences were found in the cortex, striatum, hippocampus, thalamic region and pons-medulla. These results reinforce the contention that a system involving benzodiazepine receptors may play a role in emotional behaviour.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 6276220     DOI： 10.1007/bf01948382

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  Benzodiazepine receptors in the brain as affected by different experimental stresses: the changes are small and not undirectional.

Authors:  C Braestrup; M Nielsen; E B Nielsen; M Lyon
Journal:  Psychopharmacology (Berl)       Date:  1979-11       Impact factor: 4.530

2.  Properties of 3H-diazepam binding to benzodiazepine receptors in rat cerebral cortex.

Authors:  H Möhler; T Okada
Journal:  Life Sci       Date:  1977-06-15       Impact factor: 5.037

3.  [Psychogenetic differences (RHA-vs RLA rats) in avoidance learning, open field behavior, Hebb-Williams-intelligence test and in the labyrinth exploration].

Authors:  H R Dütsch; K Bättig
Journal:  Z Exp Angew Psychol       Date:  1977

4.  Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.

Authors:  C Braestrup; R F Squires
Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205

5.  Identification of diazepam binding in intack animals.

Authors:  J F Tallman; J W Thomas; D W Gallager
Journal:  Life Sci       Date:  1979-03-05       Impact factor: 5.037

6.  Benzodiazepine receptors in "emotional" and "non-emotional" mice; comparison of four strains.

Authors:  H A Robertson
Journal:  Eur J Pharmacol       Date:  1979-06       Impact factor: 4.432

7.  Differences in benzodiazepine receptor binding in Maudsley reactive and Maudsley non-reactive rats.

Authors:  H A Robertson; I L Martin; J M Candy
Journal:  Eur J Pharmacol       Date:  1978-08-15       Impact factor: 4.432

8.  Effect of GABAergic drugs on benzodiazepine binding site sensitivity in rat cerebral cortex.

Authors:  D W Gallager; J W Thomas; J F Tallman
Journal:  Biochem Pharmacol       Date:  1978       Impact factor: 5.858

9.  Locomotor activity, defecation score and corticosterone levels during an openfield exposure: a comparison among individually and group-housed rats, and genetically selected rat lines.

Authors:  C Gentsch; M Lichtsteiner; H Feer
Journal:  Physiol Behav       Date:  1981-07

Review 10.  Receptors for the age of anxiety: pharmacology of the benzodiazepines.

Authors:  J F Tallman; S M Paul; P Skolnick; D W Gallager
Journal:  Science       Date:  1980-01-18       Impact factor: 47.728
View more
  7 in total

Review 1.  Using genetically-defined rodent strains for the identification of hippocampal traits relevant for two-way avoidance behavior: a non-invasive approach.

Authors:  H P Lipp; H Schwegler; W E Crusio; D P Wolfer; M C Leisinger-Trigona; B Heimrich; P Driscoll
Journal:  Experientia       Date:  1989-09-15

Review 2.  Genetic and pharmacological models of cholinergic supersensitivity and affective disorders.

Authors:  D H Overstreet; R W Russell; A D Crocker; J C Gillin; D S Janowsky
Journal:  Experientia       Date:  1988-06-15

3.  Differential response to cholinergic stimulation in psychogenitically selected rat lines.

Authors:  J R Martin; P Driscoll; C Gentsch
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

Review 4.  Genetic and environmental influences on behavioral and neurochemical aspects of emotionality in rats.

Authors:  C Gentsch; M Lichtsteiner; H Feer
Journal:  Experientia       Date:  1988-06-15

5.  Effects of chlordiazepoxide and imipramine on maze patrolling within two different maze configurations by psychogenetically selected lines of rats.

Authors:  J R Martin; R Oettinger; P Driscoll; R Buzzi; K Bättig
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

6.  Social isolation does not alter brain regional benzodiazepine binding site numbers, affinity and coupling in the rat.

Authors:  A Morinan; V Parker; D A Rich; P Cariuk; R W Horton
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

7.  Differential effects of early stimulation and/or perinatal flumazenil treatment in young Roman low- and high-avoidance rats.

Authors:  A Fernández-Teruel; R M Escorihuela; P Driscoll; A Tobeña; K Bättig
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.