Literature DB >> 6276008

Generation of BALB-MuSV and Ha-MuSC by type C virus transduction of homologous transforming genes from different species.

P R Andersen, S G Devare, S R Tronick, R W Ellis, S A Aaronson, E M Scolnick.   

Abstract

The nature of the cell-derived (bas) sequences of BALB-MuSV, a spontaneous mouse sarcoma virus isolate, was determined. Molecularly cloned bas sequences demonstrated no detectable homology with the onc genes of other mouse transforming viruses, but exhibited a high degree of sequence homology with the ras gene of the rat-derived Harvey murine sarcoma virus (Ha-MuSV) genome. The Ha-MuSV cell-derived sequence (ras) shared a colinear 750 bp region of homology with bas. Moreover, BALB-MuSV transformation was associated with the expression of high levels of a 21,000 dalton protein, immunologically related to the ras gene products, p21. Thus bas and ras represent retroviral transforming gene homologs that were independently transduced by mouse type C viruses from the genomes of different species.

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Year:  1981        PMID： 6276008     DOI： 10.1016/0092-8674(81)90041-6

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  24 in total

1.  Evolution of the Rho family of ras-like GTPases in eukaryotes.

Authors:  Anthony Boureux; Emmanuel Vignal; Sandrine Faure; Philippe Fort
Journal:  Mol Biol Evol       Date:  2006-10-11       Impact factor: 16.240

Review 2.  Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability.

Authors:  Yulia A Komarova; Kevin Kruse; Dolly Mehta; Asrar B Malik
Journal:  Circ Res       Date:  2017-01-06       Impact factor: 17.367

3.  Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene.

Authors:  E P Reddy; D Lipman; P R Andersen; S R Tronick; S A Aaronson
Journal:  J Virol       Date:  1985-03       Impact factor: 5.103

4.  Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents.

Authors:  D F Bowen-Pope; A Vogel; R Ross
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

5.  Regional chromosomal localization of N-ras, K-ras-1, K-ras-2 and myb oncogenes in human cells.

Authors:  O W McBride; D C Swan; S R Tronick; R Gol; D Klimanis; D E Moore; S A Aaronson
Journal:  Nucleic Acids Res       Date:  1983-12-10       Impact factor: 16.971

6.  Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins.

Authors:  J C Lacal; E Santos; V Notario; M Barbacid; S Yamazaki; H Kung; C Seamans; S McAndrew; R Crowl
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

7.  Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes.

Authors:  A Papageorge; D Lowy; E M Scolnick
Journal:  J Virol       Date:  1982-11       Impact factor: 5.103

8.  FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA.

Authors:  T Curran; G Peters; C Van Beveren; N M Teich; I M Verma
Journal:  J Virol       Date:  1982-11       Impact factor: 5.103

9.  Action of temperature-sensitive mutants of myeloproliferative sarcoma virus suggests that fibroblast-transforming and hematopoietic transforming viral properties are related.

Authors:  W Ostertag; M Freshney; K Vehmeyer; C Jasmin; G Rutter
Journal:  J Virol       Date:  1984-01       Impact factor: 5.103

10.  Chromosomal mapping of the simian sarcoma virus onc gene analogue in human cells.

Authors:  D C Swan; O W McBride; K C Robbins; D A Keithley; E P Reddy; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205
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