Literature DB >> 6275971

Epidural beta-endorphin in treatment of pain.

T Oyama, S Fukushi, T Jin.   

Abstract

Epidural administration of 3 mg of synthetic beta-endorphin produced analgesia in 10 patients with intractable pain due to disseminated cancer. Mean onset of relief of pain was 24 +/- 3 minutes and the mean duration of analgesia was 19 +/- 3 hours. The onset of analgesia produced by the epidural injection of beta-endorphin was slower and the duration less than those observed after intrathecal injection.

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Year:  1982        PMID： 6275971     DOI： 10.1007/bf03007943

Source DB:  PubMed          Journal:  Can Anaesth Soc J        ISSN： 0008-2856


  10 in total

1.  Flaccid paraparesis following obstetrical epidural anesthesia: possible role of benzyl alcohol.

Authors:  D B Craig; G G Habib
Journal:  Anesth Analg       Date:  1977 Mar-Apr       Impact factor: 5.108

2.  Pain control with epidural injection of morphine.

Authors:  M S Chayen; V Rudick; A Borvine
Journal:  Anesthesiology       Date:  1980-10       Impact factor: 7.892

3.  Spinal narcotics and respiratory depression.

Authors:  C J Glynn; L E Mather; M J Cousins; P R Wilson; J R Graham
Journal:  Lancet       Date:  1979-08-18       Impact factor: 79.321

4.  Selective epidural analgesia.

Authors:  D B Scott; J McClure
Journal:  Lancet       Date:  1979-06-30       Impact factor: 79.321

5.  Epidural morphine in treatment of pain.

Authors:  M Behar; F Magora; D Olshwang; J T Davidson
Journal:  Lancet       Date:  1979-03-10       Impact factor: 79.321

6.  Selective spinal analgesia.

Authors:  A Liolios; F H Andersen
Journal:  Lancet       Date:  1979-08-18       Impact factor: 79.321

7.  CNS depression from intrathecal morphine.

Authors:  G K Davies; C L Tolhurst-Cleaver; T L James
Journal:  Anesthesiology       Date:  1980-03       Impact factor: 7.892

8.  Opiate withdrawal syndrome following intrathecal administration of morphine.

Authors:  A S Tung; R Tenicela; P M Winter
Journal:  Anesthesiology       Date:  1980-10       Impact factor: 7.892

9.  Profound analgesic effects of beta-endorphin in man.

Authors:  T Oyama; T Jin; R Yamaya; N Ling; R Guillemin
Journal:  Lancet       Date:  1980-01-19       Impact factor: 79.321

10.  beta-Endorphin in obstetric analgesia.

Authors:  T Oyama; A Matsuki; T Taneichi; N Ling; R Guillemin
Journal:  Am J Obstet Gynecol       Date:  1980-07-01       Impact factor: 8.661
  10 in total
  2 in total

Review 1.  Peptide neuroregulators: the opioid system as a model.

Authors:  J D Barchas; C Evans; G R Elliott; P A Berger
Journal:  Yale J Biol Med       Date:  1985 Nov-Dec

Review 2.  Preclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs.

Authors:  Josef Pleticha; Lukas F Heilmann; Christopher H Evans; Aravind Asokan; Richard Jude Samulski; Andreas S Beutler
Journal:  Mol Pain       Date:  2014-09-02       Impact factor: 3.395
  2 in total

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