Literature DB >> 627565

Identification of pyruvate in S-adenosylmethionine decarboxylase from rat liver.

A A Demetriou, M S Cohn, C W Tabor, H Tabor.   

Abstract

S-Adenosylmethionine decarboxylase has been purified to homogeneity (26,000-fold) from rat liver. The enzyme has a molecular weight of 155,000 and a subunit molecular weight of 42,000. One mole of covalently bound pyruvate was found to be present per mole of enzyme subunit. This is the first mammalian enzyme found to contain covalently linked pyruvate.

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Year:  1978        PMID： 627565

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  7 in total

1.  S-adenosylmethionine decarboxylase of corn seedlings.

Authors:  Y Suzuki; E Hirasawa
Journal:  Plant Physiol       Date:  1980-12       Impact factor: 8.340

2.  Regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in a polyamine auxotrophic cell line.

Authors:  F Svensson; L Persson
Journal:  Mol Cell Biochem       Date:  1996-09-20       Impact factor: 3.396

3.  Isolation and characterization of Saccharomyces cerevisiae mutants deficient in S-adenosylmethionine decarboxylase, spermidine, and spermine.

Authors:  M S Cohn; C W Tabor; H Tabor
Journal:  J Bacteriol       Date:  1978-04       Impact factor: 3.490

4.  CGP 48664, a potent and specific S-adenosylmethionine decarboxylase inhibitor: effects on regulation and stability of the enzyme.

Authors:  F Svensson; H Mett; L Persson
Journal:  Biochem J       Date:  1997-02-15       Impact factor: 3.857

5.  Indirect evidence for a strict negative control of S-adenosyl-L-methionine decarboxylase by spermidine in rat hepatoma cells.

Authors:  P S Mamont; A M Joder-Ohlenbusch; M Nussli; J Grove
Journal:  Biochem J       Date:  1981-05-15       Impact factor: 3.857

6.  Differences between tissues in response of S-adenosylmethionine decarboxylase to administration of polyamines.

Authors:  H Pösö; A E Pegg
Journal:  Biochem J       Date:  1981-12-15       Impact factor: 3.857

7.  Comparison of inhibitors of S-adenosylmethionine decarboxylase from different species.

Authors:  A E Pegg; G Jacobs
Journal:  Biochem J       Date:  1983-08-01       Impact factor: 3.857
  7 in total

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