Literature DB >> 6275579

Allopurinol in the treatment of visceral leishmaniasis.

P A Kager, P H Rees, B T Wellde, W T Hockmeyer, W H Lyerly.   

Abstract

Allopurinol was used in the treatment of 10 patients with kala-azar. Of six patients who had previously failed to respond satisfactorily to Pentostam, "cures" were achieved in four. However, it was necessary to add Pentostam to the allopurinol in one, and another relapsed after apparent "cure" but again responded to allopurinol. The response of four patients who had had no previous treatment for kala-azar was less satisfactory.

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Year:  1981        PMID: 6275579     DOI: 10.1016/0035-9203(81)90198-x

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  11 in total

1.  Nobel lecture in physiology or medicine--1988. The purine path to chemotherapy.

Authors:  G B Elion
Journal:  In Vitro Cell Dev Biol       Date:  1989-04

2.  Kala-azar in Bihar.

Authors:  L S Prasad
Journal:  Indian J Pediatr       Date:  1987 Jan-Feb       Impact factor: 1.967

Review 3.  Interventions for Old World cutaneous leishmaniasis.

Authors:  Julio Heras-Mosteiro; Begoña Monge-Maillo; Mariona Pinart; Patricia Lopez Pereira; Ludovic Reveiz; Emely Garcia-Carrasco; Pedro Campuzano Cuadrado; Ana Royuela; Irene Mendez Roman; Rogelio López-Vélez
Journal:  Cochrane Database Syst Rev       Date:  2017-11-17

Review 4.  Leishmania and human immunodeficiency virus coinfection: the first 10 years.

Authors:  J Alvar; C Cañavate; B Gutiérrez-Solar; M Jiménez; F Laguna; R López-Vélez; R Molina; J Moreno
Journal:  Clin Microbiol Rev       Date:  1997-04       Impact factor: 26.132

Review 5.  Therapy and prophylaxis of systemic protozoan infections.

Authors:  W C Van Voorhis
Journal:  Drugs       Date:  1990-08       Impact factor: 9.546

6.  Drug targets in Leishmania.

Authors:  Bhavna Chawla; Rentala Madhubala
Journal:  J Parasit Dis       Date:  2010-10-08

7.  Suppression of Leishmania donovani by oral administration of a bis(benzyl)polyamine analog.

Authors:  R J Baumann; P P McCann; A J Bitonti
Journal:  Antimicrob Agents Chemother       Date:  1991-07       Impact factor: 5.191

8.  In vitro effects of mycophenolic acid and allopurinol against Leishmania tropica in human macrophages.

Authors:  J D Berman; H K Webster
Journal:  Antimicrob Agents Chemother       Date:  1982-06       Impact factor: 5.191

9.  Experimental visceral leishmaniasis: role of trans-aconitic acid in combined chemotherapy.

Authors:  S Kar; K Kar; P K Bhattacharya; D K Ghosh
Journal:  Antimicrob Agents Chemother       Date:  1993-11       Impact factor: 5.191

Review 10.  Interventions for Old World cutaneous leishmaniasis.

Authors:  Julio Heras-Mosteiro; Begoña Monge-Maillo; Mariona Pinart; Patricia Lopez Pereira; Ludovic Reveiz; Emely Garcia-Carrasco; Pedro Campuzano Cuadrado; Ana Royuela; Irene Mendez Roman; Rogelio López-Vélez
Journal:  Cochrane Database Syst Rev       Date:  2017-12-01
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