Literature DB >> 6275445

Nonspecific excitatory effects of morphine: reverse-order precipitated withdrawal and dose-dose interactions.

D R Stevens, W R Klemm.   

Abstract

We recently reported that, in naive mice pretreated with naloxone, morphine can cause withdrawal-like signs that seemingly are not mediated by "opiate" receptors. Such results were confirmed and extended here with another mouse strain. Repetitive vertical jumping could occur respective of injection sequence and depended on dose and dose ratio of the two drugs.

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Year:  1981        PMID： 6275445     DOI： 10.1007/bf00432189

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  7 in total

1.  Naloxone's antagonism of rigidity but not explosive motor behavior: possible evidence for two types of mechanisms underlying the actions of opiates and opioids.

Authors:  R Blair; H Cytryniak; P Shizgal; Z Amit
Journal:  Behav Biol       Date:  1978-09

2.  XVI. A homeostatic and redundancy theory of tolerance to and dependence on narcotic analgesics.

Authors:  W R Martin
Journal:  Res Publ Assoc Res Nerv Ment Dis       Date:  1968

3.  Behavioral effects of low and high acute doses of morphine in solitary mice.

Authors:  A Hecht; E Schiørring
Journal:  Psychopharmacology (Berl)       Date:  1979-06-28       Impact factor: 4.530

4.  Morphine derivatives with diminished opiate receptor potency show enhanced central excitatory activity.

Authors:  F S Labella; C Pinsky; V Havlicek
Journal:  Brain Res       Date:  1979-10-05       Impact factor: 3.252

5.  Morphine-naloxone interactions: a role for nonspecific morphine excitatory effects in withdrawal.

Authors:  D R Stevens; W R Klemm
Journal:  Science       Date:  1979-09-28       Impact factor: 47.728

6.  Opiate stimulation increases exploration in the mouse.

Authors:  R J Katz
Journal:  Int J Neurosci       Date:  1979       Impact factor: 2.292

7.  Stereospecific and nonstereospecific effects of (+)- and (-)-morphine: evidence for a new class of receptors?

Authors:  Y F Jacquet; W A Klee; K C Rice; I Iijima; J Minamikawa
Journal:  Science       Date:  1977-11-25       Impact factor: 47.728
  7 in total
  1 in total

1.  Acute morphine dependence: effects observed in shock and light discrimination tasks.

Authors:  D M Grilly; G C Gowans
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530
  1 in total

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