Literature DB >> 627467

Effect of timolol therapy on outflow facility.

J R Sonntag, G O Brindley, M B Shields.   

Abstract

A 14-week course of timolol therapy in 38 eyes with open-angle glaucoma produced a statistically significant drop (6 mm Hg) in their mean intraocular pressure but had no effect on the mean coefficient of aqueous outflow. These data are compatible with those of Zimmerman et al. obtained after a single drop of treatment and suggest that timolol reduces intraocular pressure by inhibiting aqueous production.

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Year:  1978        PMID： 627467

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN： 0146-0404            Impact factor:   4.799


  11 in total

1.  A complex interaction between topical verapamil and timolol on intraocular pressure in conscious rabbits.

Authors:  J Santafé; M J Martínez de Ibarreta; J Segarra; J Melena; M Garrido
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1996-07       Impact factor: 3.000

Review 2.  Pharmacological therapy for glaucoma: a review.

Authors:  P F Hoyng; L M van Beek
Journal:  Drugs       Date:  2000-03       Impact factor: 9.546

Review 3.  Topical dorzolamide 2%/timolol 0.5%: a review of its use in the treatment of open-angle glaucoma.

Authors:  D Ormrod; K McClellan
Journal:  Drugs Aging       Date:  2000-12       Impact factor: 3.923

4.  Effect of Timolol on Aqueous Humor Outflow Facility in Healthy Human Eyes.

Authors:  Arash Kazemi; Jay W McLaren; Matthew G J Trese; Carol B Toris; Vikas Gulati; Shan Fan; David M Reed; Tyler Kristoff; Jesse Gilbert; Sayoko E Moroi; Arthur J Sit
Journal:  Am J Ophthalmol       Date:  2019-02-19       Impact factor: 5.258

Review 5.  Ocular beta-blockers in glaucoma management. Clinical pharmacological aspects.

Authors:  A M Brooks; W E Gillies
Journal:  Drugs Aging       Date:  1992 May-Jun       Impact factor: 3.923

6.  Effects of adrenergic drugs on aqueous humour dynamics in the normal human eye. I. Salbutamol.

Authors:  R L Coakes; P B Siah
Journal:  Br J Ophthalmol       Date:  1984-06       Impact factor: 4.638

7.  Pharmacogenetics of ophthalmic topical beta-blockers.

Authors:  Duska J Sidjanin; Catherine A McCarty; Richard Patchett; Edward Smith; Russell A Wilke
Journal:  Per Med       Date:  2008       Impact factor: 2.512

8.  Brain natriuretic peptide: identification of a second natriuretic peptide in human aqueous humour.

Authors:  J Salzmann; D Flitcroft; C Bunce; D Gordon; R Wormald; C Migdal
Journal:  Br J Ophthalmol       Date:  1998-07       Impact factor: 4.638

9.  Timolol in operated closed-angle glaucoma.

Authors:  C I Phillips
Journal:  Br J Ophthalmol       Date:  1980-04       Impact factor: 4.638

10.  Study of the additive effect of timolol and epinephrine in lowering intraocular pressure.

Authors:  J V Thomas; D L Epstein
Journal:  Br J Ophthalmol       Date:  1981-09       Impact factor: 4.638
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