Literature DB >> 6274376

Experimental ulcerative herpetic keratitis. IV. Preliminary observations on the efficacy of a herpes simplex subunit vaccine.

C A Carter, C E Hartley, G R Skinner, S P Turner, D L Easty.   

Abstract

Systemic vaccination of rabbits with an inactivated type 1 virus subunit vaccine induced humoral and cell-mediated immune responses. Following ocular infection with type 1 herpes virus corneal ulceration and virus excretion were reduced in the vaccinated rabbits.

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Year:  1981        PMID: 6274376      PMCID: PMC1039636          DOI: 10.1136/bjo.65.10.679

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  15 in total

1.  A sensitive and precise plaque assay for herpes virus.

Authors:  W C RUSSELL
Journal:  Nature       Date:  1962-09-08       Impact factor: 49.962

2.  Effect of immunization on acute and latent infections of vaginouterine tissue with herpes simplex virus types 1 and 2.

Authors:  M A Walz; R W Price; K Hayashi; B J Katz; A L Notkins
Journal:  J Infect Dis       Date:  1977-05       Impact factor: 5.226

3.  Serological relatedness of herpes simplex viruses. Type-specificity of antibody response.

Authors:  G R Skinner; M E Thouless; S Trueman; J Edwards; A J Gibbs
Journal:  Immunology       Date:  1976-09       Impact factor: 7.397

4.  Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence.

Authors:  I MACPHERSON; M STOKER
Journal:  Virology       Date:  1962-02       Impact factor: 3.616

5.  Differentiation between type 1 and type 2 strains of herpes simplex virus by an indirect immunofluorescent technique.

Authors:  L Geder; G R Skinner
Journal:  J Gen Virol       Date:  1971-08       Impact factor: 3.891

6.  Precipitating antibodies to herpes simplex virus in human sera: prevalence of antibody to common antigen (band II).

Authors:  G R Skinner; J Taylor; J Edwards
Journal:  Intervirology       Date:  1974       Impact factor: 1.763

7.  Topical vaccine therapy in herpetic keratitis.

Authors:  R Pollikoff
Journal:  Lancet       Date:  1970-05-16       Impact factor: 79.321

8.  Protection from oral herpes simplex virus infection by a nucleic acid-free virus vaccine.

Authors:  E N Kitces; P S Morahan; J G Tew; B K Murray
Journal:  Infect Immun       Date:  1977-06       Impact factor: 3.441

9.  Efficacy of herpes simplex virus type 1 immunization in protecting against acute and latent infection by herpes simplex virus type 2 in mice.

Authors:  R R McKendall
Journal:  Infect Immun       Date:  1977-05       Impact factor: 3.441

10.  Double--blind clinical trial of adenine arabinoside and idoxuridine in herpetic corneal ulcers.

Authors:  R H Markham; C Carter; M A Scobie; C Metcalf; D L Easty
Journal:  Trans Ophthalmol Soc U K       Date:  1977-07
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  4 in total

1.  Report of twelve years experience in open study of Skinner herpes simplex vaccine towards prevention of herpes genitalis.

Authors:  G R Skinner; C Fink; J Melling; C Wiblin; B Thornton; J Hallworth; W Gardner; P McLeish; C Hartley; A Buchan
Journal:  Med Microbiol Immunol       Date:  1992       Impact factor: 3.402

2.  Follow-up report on 50 subjects vaccinated against herpes genitalis with Skinner vaccine.

Authors:  G R Skinner; C G Fink; M Cowan; A Buchan; A Fuller; C E Hartley; J Durham; C Wiblin; J Melling
Journal:  Med Microbiol Immunol       Date:  1987       Impact factor: 3.402

3.  Preparation and immunogenicity of vaccine Ac NFU1 (S-) MRC towards the prevention of herpes genitalis.

Authors:  G R Skinner; C B Woodman; C E Hartley; A Buchan; A Fuller; J Durham; M Synnott; J C Clay; J Melling; C Wiblin; J Wilkins
Journal:  Br J Vener Dis       Date:  1982-12

4.  Immunogenicity and protective efficacy in a rhesus monkey model of vaccine Ac NFUi(S-) MRC against primary type 2 herpes simplex virus infection.

Authors:  G R Skinner; A Buchan; D Williams; J Marsden; C Hartley; G Wilbanks; M Turyk; E S Namkoong
Journal:  Br J Exp Pathol       Date:  1982-08
  4 in total

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