| Literature DB >> 6272715 |
G Mugnai, R Coppini, D Tombaccini, A Fallani, S Ruggieri.
Abstract
The structural analysis of neutral glycolipids and gangliosides of the SV40 transformed Balb/c3T3 cells (SV3T3 cells) and concanavalin A-selected SV3T3 revertant cells, both compared with untransformed Balb/c3T3 cells, has shown: (i) a content of neutral glycolipids in revertant cells near to that found in the untransformed parental cells; (ii) a similar decrease of the higher gangliosides in transformed and revertant cells; (iii) a content of ganglioside GM3 in revertant cells much higher than that found in both SV3T3 and untransformed Balb/3T3 cells. The possible role of ganglioside GM3 in growth control is discussed.Entities:
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Year: 1981 PMID: 6272715 PMCID: PMC1162701 DOI: 10.1042/bj1931025
Source DB: PubMed Journal: Biochem J ISSN: 0264-6021 Impact factor: 3.857