Literature DB >> 6272545

Effect of pituitary intermediate lobe extract on steroid production by the isolated zona glomerulosa and fasciculata cells.

K S Szalay.   

Abstract

The effect of intermediate lobe extract (ILE) on aldosterone and corticosterone production of the zona glomerulosa cells and on corticosterone production of the zona fasciculata cells was investigated. The slope of the dose-response curve of ILE dilution was steeper than that of alpha h 1-39 ACTH measured on zona glomerulosa steroid production. The ED50 of both ILE and ACTH was lower when measured on zona glomerulosa than on zona fasciculata steroid production. It is supposed that a hormone (or some other substance) in ILE alters the sensitivity to ACTH of the zona glomerulosa cells.

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Year:  1981        PMID： 6272545

Source DB:  PubMed          Journal:  Acta Physiol Acad Sci Hung        ISSN： 0001-6756


  5 in total

1.  Stereological and functional investigations on isolated adrenocortical cells: zona fasciculata/reticularis cells of chronically ACTH-treated rats.

Authors:  P G Andreis; P Rebuffat; A S Belloni; G Neri; L Cavallini; G Gottardo; G Mazzocchi; A Coi; L K Malendowicz; G G Nussdorfer
Journal:  Cell Tissue Res       Date:  1989-10       Impact factor: 5.249

2.  A mechanism of the influence of interleukin-1 on blood glucocorticoid level: absence of a direct effect of interleukin-1 on adrenal cortical cells.

Authors:  E G Rybakina; K Salai; E A Korneva; E K Shkhinek; M P Lesnikova
Journal:  Neurosci Behav Physiol       Date:  1991 Mar-Apr

3.  Stereological and functional investigations on isolated adrenocortical cells. III. Zona glomerulosa cells of chronically ACTH-treated rats.

Authors:  P G Andreis; G Neri; P Rebuffat; G Gottardo; G Mazzocchi; G G Nussdorfer
Journal:  J Anat       Date:  1990-02       Impact factor: 2.610

4.  Effect of histamine on corticosteroid secretion of isolated human and rat adrenocortical cells.

Authors:  E Orsó; K S Szalay; I E Tóth; D Szabó; E Stark; T Fehér; F Perner; M Hidvégi
Journal:  Inflamm Res       Date:  1995-04       Impact factor: 4.575

5.  The effects of ageing on the morphology and function of the zonae fasciculata and reticularis of the rat adrenal cortex.

Authors:  P Rebuffat; A S Belloni; S Rocco; P G Andreis; G Neri; L K Malendowicz; G Gottardo; G Mazzocchi; G G Nussdorfer
Journal:  Cell Tissue Res       Date:  1992-11       Impact factor: 5.249
  5 in total

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