| Literature DB >> 6272394 |
J B Penney, H S Pan, A B Young, K A Frey, G W Dauth.
Abstract
A simple quantitative autoradiographic technique for the study of neurotransmitter receptors that includes the use of a tritium-sensitive film permits saturation, kinetic, and competition studies of brain samples as small as 0.01 cubic millimeter. This technique was used to study [3H]muscimol binding in rat brain. Unilateral gamma-aminobutyric acid receptor supersensitivity was observed in the substantia nigra pars reticulata after production of localized lesions of the ipsilateral corpus striatum.Entities:
Mesh:
Substances:
Year: 1981 PMID: 6272394 DOI: 10.1126/science.6272394
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728