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Literature DB >> 6272200

The conformation of adenovirus VAI-RNA in solution.

Abstract

The secondary structure of an adenovirus associated low molecular weight RNA (VAI-RNA) has been studied by partial digestion with T1-RNase and S1-endonuclease followed by T1-fingerprint analysis. The empirical secondary structure has been compared with two computer generated models based on minimal free energy of the structure. The results suggest that VAI-RNA in solution has a compact structure with a free energy of around -60 kcal with two stems and four bulge regions. The implication of this structure for the function of VAI-RNA is discussed.

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Year: 1981 PMID： 6272200 PMCID： PMC327432 DOI： 10.1093/nar/9.17.4239

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

24 in total

1. Studies of low molecular weight RNA from cells infected with adenovirus 2. III. The sequence of the promoter for VA-RNA I.

Authors: J Pan; M L Celma; S M Weissman
Journal: J Biol Chem Date: 1977-12-25 Impact factor: 5.157

10. Detection of a cellular polypeptide associated with adenovirus-coded VA RNA using in vitro labeling of proteins cross-linked to RNA.

Authors: C van Eekelen; H Buijtels; T Linné; R Ohlsson; L Philipson; W van Venrooij
Journal: Nucleic Acids Res Date: 1982-05-25 Impact factor: 16.971

The conformation of adenovirus VAI-RNA in solution.

1. Studies of low molecular weight RNA from cells infected with adenovirus 2. III. The sequence of the promoter for VA-RNA I.

2. A new method for sequencing DNA.

3. Structure of yeast phenylalanine tRNA at 3 A resolution.

4. Improved estimation of secondary structure in ribonucleic acids.

5. Nucleotide sequence of an RNA from cells infected with adenovirus 2.

6. The low molecular weight of RNAs of adenovirus 2-infected cells.

7. A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2.

8. Low molecular weight viral RNAs transcribed by RNA polymerase III during adenovirus 2 infection.

9. The conformation of chicken, rat and human U1A RNAs in solution.

10. Genes for VA-RNA in adenovirus 2.

1. Binding of the adenovirus VAI RNA to the interferon-induced 68-kDa protein kinase correlates with function.

2. A model for the initiation of translation at the late stage after infection by adenoviruses.

3. Structural analyses of EBER1 and EBER2 ribonucleoprotein particles present in Epstein-Barr virus-infected cells.

4. Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI.

5. Functional dissection of adenovirus VAI RNA.

6. Small nuclear RNAs are encoded in the nontranscribed region of ribosomal spacer DNA.

7. In vitro transcription of two Epstein-Barr virus specified small RNA molecules.

8. VA RNAs from avian and human adenoviruses: dramatic differences in length, sequence, and gene location.

9. Multiple proteins bind to VA RNA genes of adenovirus type 2.

10. Detection of a cellular polypeptide associated with adenovirus-coded VA RNA using in vitro labeling of proteins cross-linked to RNA.