Literature DB >> 6271872

Clonal analysis of the BALB/c T cell proliferative response to apo beef cytochrome c.

G Corradin, R H Zubler, H D Engers.   

Abstract

Murine T cell clones that proliferated specifically in response to the protein antigen apo cytochrome c were derived and maintained in continuous culture. Two distinct clonotypes were observed with respect to the proliferative responses observed when a variety of peptides prepared from several species of cytochrome c were tested. These 2 clonotypes appeared to recognize 2 different regions in the cytochrome c molecule. Only 1 of the 2 clonotypes tested demonstrated helper cell activity for antibody formation in vitro.

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Year:  1981        PMID： 6271872

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  3 in total

1.  The heme moiety of cytochrome c is an autoreactive Ir gene-restricted T cell epitope.

Authors:  H M Cooper; G Corradin; Y Paterson
Journal:  J Exp Med       Date:  1988-09-01       Impact factor: 14.307

2.  The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones.

Authors:  A Finnegan; M A Smith; J A Smith; J Berzofsky; D H Sachs; R J Hodes
Journal:  J Exp Med       Date:  1986-09-01       Impact factor: 14.307

3.  Two minor determinants of myelin basic protein induce experimental allergic encephalomyelitis in SJL/J mice.

Authors:  D H Kono; J L Urban; S J Horvath; D G Ando; R A Saavedra; L Hood
Journal:  J Exp Med       Date:  1988-07-01       Impact factor: 14.307
  3 in total

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