Literature DB >> 6271253

Extracellular folate deaminase of Dictyostelium discoideum.

R L Bernstein, M Tabler, D Vestweber, R Van Driel.   

Abstract

Folate deaminase released from cells of Dictyostelium discoideum is heterogeneous with respect to molecular weight and stability at 60 degrees C. The most heat-stable component isoelectrofocuses in a broad band at approx. pH 6. The Km value of this component for folate is approx. 7 x 10(-7)M and Mr approx. 40 000. The major portion if not all of the deaminase binds to immobilized concanavalin A and lentil lectin. Extracellular folate deaminase has a pH-optimum of approx. pH 6.0. This is higher than that of lysosomal enzymes, which are also glycoproteins released into the extracellular medium.

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Year:  1981        PMID： 6271253     DOI： 10.1016/0304-4165(81)90099-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  6 in total

1.  Identification of a pterin as the acrasin of the cellular slime mold Dictyostelium lacteum.

Authors:  P J Van Haastert; R J De Wit; Y Grijpma; T M Konijn
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

2.  Characterization of the folic acid C9-N10-cleaving enzyme of Dictyostelium minutum V3.

Authors:  R J De Wit; R J van der Velden; T M Konijn
Journal:  J Bacteriol       Date:  1983-05       Impact factor: 3.490

3.  Genetic and physiologic modulation of the prestarvation response in Dictyostelium discoideum.

Authors:  V Burdine; M Clarke
Journal:  Mol Biol Cell       Date:  1995-03       Impact factor: 4.138

4.  Induction by folate and folate analogs of extracellular and membrane-bound phosphodiesterase from Dictyostelium discoideum.

Authors:  P van Ophem; R van Driel
Journal:  J Bacteriol       Date:  1985-10       Impact factor: 3.490

5.  Self-Generated Chemoattractant Gradients: Attractant Depletion Extends the Range and Robustness of Chemotaxis.

Authors:  Luke Tweedy; David A Knecht; Gillian M Mackay; Robert H Insall
Journal:  PLoS Biol       Date:  2016-03-16       Impact factor: 8.029

Review 6.  Moving the Research Forward: The Best of British Biology Using the Tractable Model System Dictyostelium discoideum.

Authors:  Robin S B Williams; Jonathan R Chubb; Robert Insall; Jason S King; Catherine J Pears; Elinor Thompson; Cornelis J Weijer
Journal:  Cells       Date:  2021-11-05       Impact factor: 7.666
  6 in total

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