Literature DB >> 6270352

Lack of AKR ecotropic provirus amplification in AKR leukemic thymuses.

F K Yoshimura, M Breda.   

Abstract

A DNA fragment from the 3' region of a molecularly cloned AKR ecotropic provirus was identified to be specific for the AKR ecotropic murine leukemia virus (MuLV). This selected DNA fragment was used to analyze the integrated MuLV proviruses in normal and leukemic tissue DNAs of AKR mice. In comparison with a DNA fragment from the 5' region of the cloned AKR genome or one representing the entire genome, this selected probe hybridized to only a few MuLV proviruses. By comparing transformed and nontransformed tissue DNAs, it appeared that no amplification of proviral sequences related to the AKR ecotropic MuLV had occurred in thymomas of AKR mice during the development of leukemia in these animals. Analysis of the AKR ecotropic MuLV proviruses revealed a significant degree of polymorphism for these sequences among individuals in the AKR/J strain of mouse.

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Year:  1981        PMID： 6270352      PMCID： PMC171313     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  24 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Biochemical evidence that MCF murine leukemia viruses are envelope (env) gene recombinants.

Authors:  J H Elder; J W Gautsch; F C Jensen; R A Lerner; J W Hartley; W P Rowe
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

3.  Characterization and mapping of RNase T1-resistant oligonucleotides derived from the genomes of Akv and MCF murine leukemia viruses.

Authors:  J Rommelaere; D V Faller; N Hopkins
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

4.  Efficeint transcription of RNA into DNA by avian sarcoma virus polymerase.

Authors:  J M Taylor; R Illmensee; J Summers
Journal:  Biochim Biophys Acta       Date:  1976-09-06

5.  Genetic mapping of a murine leukemia virus-inducing locus of AKR mice.

Authors:  W P Rowe; J W Hartley; T Bremner
Journal:  Science       Date:  1972-11-24       Impact factor: 47.728

6.  A new class of murine leukemia virus associated with development of spontaneous lymphomas.

Authors:  J W Hartley; N K Wolford; L J Old; W P Rowe
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

7.  AKR murine leukemia virus genome: frequency of sequences in DNA of high-, low-, and non-virus-yielding mouse strains.

Authors:  D R Lowy; S K Chattopadhyay; N M Teich; W P Rowe; A S Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205

8.  Increase of AKR-specific sequences in tumor tissues of leukemic AKR mice.

Authors:  A Berns; R Jaenisch
Journal:  Proc Natl Acad Sci U S A       Date:  1976-07       Impact factor: 11.205

9.  Nucleotide sequence of the rightward operator of phage lambda.

Authors:  T Maniatis; A Jeffrey; D G Kleid
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

10.  Studies of genetic transmission of murine leukemia virus by AKR mice. I. Crosses with Fv-1 n strains of mice.

Authors:  W P Rowe
Journal:  J Exp Med       Date:  1972-11-01       Impact factor: 14.307
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  17 in total

1.  SMX-1 virus-induced inhibition of ecotropic and recombinant proviral sequence amplification in thymuses of AKR mice.

Authors:  D L Buchhagen; E Stockert
Journal:  J Virol       Date:  1984-11       Impact factor: 5.103

2.  Identification of ecotropic proviral sequences in high- and low-ecotropic-virus-producing mouse strains.

Authors:  J L Moore; H W Chan
Journal:  J Virol       Date:  1982-09       Impact factor: 5.103

3.  Identification of a DNA fragment from a molecularly cloned mink cell focus-inducing murine leukemia virus specific for xenotropic virus-related sequences.

Authors:  F K Yoshimura
Journal:  J Virol       Date:  1982-07       Impact factor: 5.103

4.  Somatically acquired recombinant murine leukemia proviruses in thymic leukemias of AKR/J mice.

Authors:  W Herr; W Gilbert
Journal:  J Virol       Date:  1983-04       Impact factor: 5.103

5.  Molecular cloning of a highly leukemogenic, ecotropic retrovirus from an AKR mouse.

Authors:  J Lenz; R Crowther; S Klimenko; W Haseltine
Journal:  J Virol       Date:  1982-09       Impact factor: 5.103

6.  Differential cell killing by lymphomagenic murine leukemia viruses occurs independently of p53 activation and mitochondrial damage.

Authors:  Suparna Nanua; Fayth K Yoshimura
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

7.  Novel class of mouse mammary tumor virus-related DNA sequences found in all species of Mus, including mice lacking the virus proviral genome.

Authors:  R Callahan; W Drohan; D Gallahan; L D'Hoostelaere; M Potter
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

8.  Ecotropic murine leukemia virus DNA content of normal and lymphomatous tissues of BXH-2 recombinant inbred mice.

Authors:  N A Jenkins; N G Copeland; B A Taylor; H G Bedigian; B K Lee
Journal:  J Virol       Date:  1982-05       Impact factor: 5.103

9.  Variation in the number of copies and in the genomic organization of ecotropic murine leukemia virus proviral sequences in sublines of AKR mice.

Authors:  C E Buckler; S P Staal; W P Rowe; M A Martin
Journal:  J Virol       Date:  1982-08       Impact factor: 5.103

10.  Linkage of the Fv-2 gene to a newly reinserted ecotropic retrovirus in Fv-2 congenic mice.

Authors:  M Mowat; A Bernstein
Journal:  J Virol       Date:  1983-09       Impact factor: 5.103
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