Literature DB >> 6269706

Stress and beta-adrenergic receptor binding in the rat's brain.

S Nomura, M Watanabe, N Ukei, T Nakazawa.   

Abstract

The effect of acute and chronic electric shocks on beta-adrenergic receptor binding in the rat's brain was investigated. Beta-adrenergic receptor subsensitivity in the cortex was induced by chronic shocks, but not by acute shocks. This reduction appears to be due to a decreased number of receptors. It seems that stress, by increasing intrasynaptic norepinephrine levels resulting from an accelerated turnover rate, causes beta-adrenergic receptor subsensitivity.

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Year:  1981        PMID： 6269706     DOI： 10.1016/0006-8993(81)91133-1

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  6 in total

1.  Transcranial magnetic stimulation downregulates beta-adrenoreceptors in rat cortex.

Authors:  A Fleischmann; A Sternheim; A M Etgen; C Li; N Grisaru; R H Belmaker
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

2.  Monoaminergic structures of the hypothalamus under chronic stress conditions.

Authors:  M S Konstantinova; I P Smorodina
Journal:  Neurosci Behav Physiol       Date:  1986 Nov-Dec

3.  Effect of repeated administration of novel stressors on central beta adrenoceptors.

Authors:  M P Areso; A Frazer
Journal:  J Neural Transm Gen Sect       Date:  1991

4.  Previous chronic chlorimipramine treatment did not modify some physiological responses to acute and chronic stress in rats.

Authors:  A Armario; C García-Marquez; M Giralt
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

5.  Too much of a good thing: blocking noradrenergic facilitation in medial prefrontal cortex prevents the detrimental effects of chronic stress on cognition.

Authors:  Julianne D Jett; David A Morilak
Journal:  Neuropsychopharmacology       Date:  2012-11-07       Impact factor: 7.853

Review 6.  Mechanisms of the blunting of the sympatho-adrenal response: a theory.

Authors:  B Parekh
Journal:  Curr Diabetes Rev       Date:  2009-05
  6 in total

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