| Literature DB >> 6269406 |
W J Strittmatter, F Hirata, J Axelrod.
Abstract
Stimulation of the beta-adrenergic receptor increases the enzymatic methylation of membrane phospholipids. Increased synthesis of phosphatidyl-N-monomethylethanolamine by methyltransferase I increases fluidity and enhances the ability of the beta-adrenergic receptor to couple with adenylate cyclase. The number of beta-adrenergic receptors can be regulated by the rate of synthesis and of degradation of phosphatidylcholine formed by transmethylation.Entities:
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Year: 1981 PMID： 6269406
Source DB: PubMed Journal: Adv Cyclic Nucleotide Res ISSN： 0084-5930