Literature DB >> 6268804

Mapping of alterations in noninfectious proviruses of spleen necrosis virus.

J J O'Rear, H M Temin.   

Abstract

Ten recombinant lambda phage containing proviruses of spleen necrosis virus (SNV) were previously obtained. Six of the proviruses are infectious and four are not infectious in infectious DNA assays. In this paper, we show that these noninfectious proviruses are not infectious because of alterations in the viral DNA. We constructed recombinants between infectious and noninfectious proviruses and tested these recombinants in an infectious DNA assay. In addition, we carried out cotransfection of a noninfectious provirus with a restriction endonuclease-generated fragment of viral DNA. The alterations in the viral DNA resulting in lack of infectivity were mapped to regions of viral DNA of 1 to 2 kilobase pairs. These results and other biochemical data indicate that alterations in retrovirus proviruses occur at a high frequency.

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Year:  1981        PMID： 6268804      PMCID： PMC171273     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  29 in total

1.  Replication of reticuloendotheliosis viruses in cell culture: chronic infection.

Authors:  H M Temin; V K Kassner
Journal:  J Gen Virol       Date:  1975-06       Impact factor: 3.891

2.  Mapping temperature-sensitive mutants of simian virus 40: rescue of mutants by fragments of viral DNA.

Authors:  C J Lai; D Nathans
Journal:  Virology       Date:  1974-08       Impact factor: 3.616

3.  Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis.

Authors:  P A Sharp; B Sugden; J Sambrook
Journal:  Biochemistry       Date:  1973-07-31       Impact factor: 3.162

4.  Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol.

Authors:  D B Clewell
Journal:  J Bacteriol       Date:  1972-05       Impact factor: 3.490

5.  A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors:  F L Graham; A J van der Eb
Journal:  Virology       Date:  1973-04       Impact factor: 3.616

6.  A system for mapping DNA sequences in the chromosomes of Drosophila melanogaster.

Authors:  P C Wensink; D J Finnegan; J E Donelson; D S Hogness
Journal:  Cell       Date:  1974-12       Impact factor: 41.582

7.  Stimulation by cyclic adenosine monophosphate of plasmid deoxyribonucleic acid replication and catabolite repression of the plasmid deoxyribonucleic acid-protein relaxation complex.

Authors:  L Katz; D T Kingsbury; D R Helinski
Journal:  J Bacteriol       Date:  1973-05       Impact factor: 3.490

8.  Infectious rous sarcoma virus and reticuloendotheliosis virus DNAs.

Authors:  G M Cooper; H M Temin
Journal:  J Virol       Date:  1974-11       Impact factor: 5.103

9.  Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity.

Authors:  C Y Kang; H M Temin
Journal:  J Virol       Date:  1973-12       Impact factor: 5.103

10.  Replication of reticuloendotheliosis viruses in cell culture: acute infection.

Authors:  H M Temin; V K Kassner
Journal:  J Virol       Date:  1974-02       Impact factor: 5.103
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  12 in total

1.  Sequence instability in the long terminal repeats of avian spleen necrosis virus and reticuloendotheliosis virus.

Authors:  G Notani; W Sauerbier
Journal:  J Mol Evol       Date:  1987       Impact factor: 2.395

2.  Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues.

Authors:  R Jaenisch; A Schnieke; K Harbers
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

3.  Spontaneous variation and synthesis in the U3 region of the long terminal repeat of an avian retrovirus.

Authors:  K Shimotohno; H M Temin
Journal:  J Virol       Date:  1982-01       Impact factor: 5.103

4.  Spontaneous changes in nucleotide sequence in proviruses of spleen necrosis virus, an avian retrovirus.

Authors:  J J O'Rear; H M Temin
Journal:  Proc Natl Acad Sci U S A       Date:  1982-02       Impact factor: 11.205

5.  Infectivity and structure of molecular clones obtained from two genetically transmitted Moloney leukemia proviral genomes.

Authors:  K Harbers; A Schnieke; H Stuhlmann; R Jaenisch
Journal:  Nucleic Acids Res       Date:  1982-04-24       Impact factor: 16.971

6.  Genome of reticuloendotheliosis virus: characterization by use of cloned proviral DNA.

Authors:  N R Rice; R R Hiebsch; M A Gonda; H R Bose; R V Gilden
Journal:  J Virol       Date:  1982-04       Impact factor: 5.103

7.  Cloning of two genetically transmitted Moloney leukemia proviral genomes: correlation between biological activity of the cloned DNA and viral genome activation in the animal.

Authors:  I Chumakov; H Stuhlmann; K Harbers; R Jaenisch
Journal:  J Virol       Date:  1982-06       Impact factor: 5.103

8.  Endogenous Moloney leukemia virus in nonviremic Mov substrains of mice carries defects in the proviral genome.

Authors:  A Schnieke; H Stuhlmann; K Harbers; I Chumakov; R Jaenisch
Journal:  J Virol       Date:  1983-02       Impact factor: 5.103

9.  Characterization of reticuloendotheliosis virus strain T DNA and isolation of a novel variant of reticuloendotheliosis virus strain T by molecular cloning.

Authors:  I S Chen; T W Mak; J J O'Rear; H M Temin
Journal:  J Virol       Date:  1981-12       Impact factor: 5.103

10.  DNAs of two molecularly cloned endogenous ecotropic proviruses are poorly infectious in DNA transfection assays.

Authors:  N G Copeland; H G Bedigian; C Y Thomas; N A Jenkins
Journal:  J Virol       Date:  1984-02       Impact factor: 5.103
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