Literature DB >> 6268014

The presence of intranuclear lipid inclusions in hepatocytes of mice after chronic ingestion of polybrominated biphenyl.

L J Martino, N A Wilson-Martino, K F Benitz.   

Abstract

Electron microscopic study of livers from mice fed 167 ppm polybrominated biphenyl (PBB) for 12 weeks showed hepatocytes with nuclei containing varied amounts of lipid inclusions. The inclusions appeared as spherical vacuoles free in the nuclear matrix. This is the first report of the induction of lipid inclusions within the nucleus by a halogenated hydrocarbon.

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Year:  1981        PMID： 6268014     DOI： 10.1007/bf00332357

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  10 in total

1.  Octabromobiphemyl-induced ultrastructural changes in rat liver.

Authors:  K P Lee; R R Hebert; H Sherman; J G Aftosmis; R S Waritz
Journal:  Arch Environ Health       Date:  1975-09

2.  Bromine tissue residue and hepatotoxic effects of octabromobiphenyl in rats.

Authors:  K P Lee; R R Herbert; H Sherman; J G Aftosmis; R S Waritz
Journal:  Toxicol Appl Pharmacol       Date:  1975-10       Impact factor: 4.219

3.  Comparative toxicity of polychlorinated biphenyl and polybrominated biphenyl in the rat liver: light and electron microscopic alterations after subacute dietary exposure.

Authors:  L Kasza; M A Weinberger; D E Hinton; B F Trump; C Patel; L Friedman; L H Garthoff
Journal:  J Environ Pathol Toxicol       Date:  1978 Jan-Feb

4.  Morphological and biochemical changes in the liver of rats fed polychlorinated biphenyls.

Authors:  J R Allen; L J Abrahamson
Journal:  Arch Environ Contam Toxicol       Date:  1973-10       Impact factor: 2.804

5.  Fatty inclusions and microcysts. Thioacetamide induced fatty inclusions in nuclei of mouse liver cells and hepatoma cells.

Authors:  E B Smith; J S Nosanchuk; B Schnitzer; R L Swarm
Journal:  Arch Pathol       Date:  1968-02

6.  Fine structure of transplantable hepatomas of the rat.

Authors:  Z Hruban; H Swift; M Rechcigl
Journal:  J Natl Cancer Inst       Date:  1965-09       Impact factor: 13.506

7.  Ultrastructure of human primary hepatic carcinoma.

Authors:  C Toker; N Trevino
Journal:  Cancer       Date:  1966-11       Impact factor: 6.860

8.  Acute, subacute, and residual effects of polychlorinated biphenyl (pcb) in rats. II. Pathology and electron microscopy of liver and serum enzyme study.

Authors:  L Kasza; M A Weinberger; C Carter; D E Hinton; B F Trump; E A Brouwer
Journal:  J Toxicol Environ Health       Date:  1976-05

9.  Electron microscopy of intranuclear inclusions found in human and rat liver parenchymal cells.

Authors:  W J FRAJOLA; M H GREIDER; R G KLEINFELD
Journal:  J Biophys Biochem Cytol       Date:  1956-07-25

10.  An electron microscope study of intranuclear inclusions in mouse liver and hepatoma.

Authors:  E H LEDUC; J W WILSON
Journal:  J Biophys Biochem Cytol       Date:  1959-12
  10 in total

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