Coronary angiography with iohexol and other contrast media in the dog. I. Electrocardiographic alterations.

In the dog the effects on ECG at coronary angiography with the non-ionic contrast media iohexol and metrizamide and the ionic medium diatrizoate were compared. Iohexol and metrizamide produced less prolongation of the PQ time during left-sided infusions and less prolongation of the QT time during right-sided infusions. Thus, as a cardiovascular contrast medium iohexol may cause fewer incidences of heart block and ventricular fibrillation than ionic contrast media.