Literature DB >> 6267672

Effect of 1 alpha-hydroxyvitamin D3 on the glucose and calcium metabolism in genetic obese mice.

H Kawashima, A Castro.   

Abstract

In summary, it is demonstrated, for the first time, that there is a marked reduction of bone mass in ob/ob mice and this was restored by the treatment with 1 alpha-OH-D3. The effect of the sterol was accompanied by the improvement of hyperglycemia, hyperinsulinemia, and fat tissue responsibility to hormones. Thus, it is of interest to study obesity in terms of calcium homeostasis.

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Year:  1981        PMID: 6267672

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  3 in total

1.  A potential role for the myeloid lineage in leptin-regulated bone metabolism.

Authors:  E L Scheller; J Song; M I Dishowitz; K D Hankenson; P H Krebsbach
Journal:  Horm Metab Res       Date:  2011-12-28       Impact factor: 2.936

2.  Mitochondrial Ca2+ transport in lean and genetically obese (ob/ob) mice.

Authors:  D R Fraser; P Trayhurn
Journal:  Biochem J       Date:  1983-07-15       Impact factor: 3.857

3.  Pancreatic secretion in man with subclinical vitamin D deficiency.

Authors:  B L Nyomba; J Auwerx; V Bormans; T L Peeters; W Pelemans; J Reynaert; R Bouillon; G Vantrappen; P De Moor
Journal:  Diabetologia       Date:  1986-01       Impact factor: 10.122

  3 in total

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