Literature DB >> 6267173

Protection of mice by an apathogenic strain HSV-1 against lethal infection by a pathogenic strain of HSV-1.

C H Schröeder, H Engler, H Kirchner.   

Abstract

DBA/2 and C57BL/6 mice were infected intraperitoneally with two different strains of herpes simplex virus type 1, HSV-1 ANG and HSV-1 WAL. Unlike HSV-1 WAL, HSV-1 ANG was apathogenic by this mode of infection. Furthermore, infection with HSV-1 ANG protected mice of both inbred strains against infections with lethal doses of pathogenic HSV-1 WAL. This protection was observed when the apathogenic virus was given with the pathogenic virus or 4 to 24 h before it.

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Year:  1981        PMID： 6267173     DOI： 10.1099/0022-1317-52-1-159

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  17 in total

1.  Passive immune protection by herpes simplex virus-specific monoclonal antibodies and monoclonal antibody-resistant mutants altered in pathogenicity.

Authors:  G Kümel; H C Kaerner; M Levine; C H Schröder; J C Glorioso
Journal:  J Virol       Date:  1985-12       Impact factor: 5.103

2.  In vitro cytopathology and pathogenicity to inbred mice shown by five variants of a laboratory strain of type 1 herpes simplex virus.

Authors:  M Yamada; F Uno; S Nii
Journal:  Arch Virol       Date:  1986       Impact factor: 2.574

3.  Species selective interaction of Alphaherpesvirinae with the "unspecific" immune system of the host.

Authors:  H P Huemer; C Larcher; S van Drunen Littel-van den Hurk; L A Babiuk
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

4.  Pathogenesis of genital herpes simplex virus infection in mice. III. Comparison of the virulence of wild and mutant strains.

Authors:  K E Schneweis; H Forstbauer; M Olbrich; M Tag
Journal:  Med Microbiol Immunol       Date:  1984       Impact factor: 3.402

5.  Replication of HSV-1 in murine peritoneal macrophages: comparison of various virus strains with different properties.

Authors:  J Görtz; B Brake; V Härle-Grupp; D Falke
Journal:  Arch Virol       Date:  1984       Impact factor: 2.574

6.  Immunogenicity of herpes simplex virus glycoproteins gC and gB and their role in protective immunity.

Authors:  J Glorioso; C H Schröder; G Kumel; M Szczesiul; M Levine
Journal:  J Virol       Date:  1984-06       Impact factor: 5.103

7.  Herpes simplex virus glycoprotein C: molecular mimicry of complement regulatory proteins by a viral protein.

Authors:  H P Huemer; Y Wang; P Garred; V Koistinen; S Oppermann
Journal:  Immunology       Date:  1993-08       Impact factor: 7.397

8.  Genetic variability of herpes simplex virus: development of a pathogenic variant during passaging of a nonpathogenic herpes simplex virus type 1 virus strain in mouse brain.

Authors:  H C Kaerner; C H Schröder; A Ott-Hartmann; G Kümel; H Kirchner
Journal:  J Virol       Date:  1983-04       Impact factor: 5.103

9.  Factors influencing the interaction of herpes simplex virus glycoprotein C with the third component of complement.

Authors:  H P Huemer; C Larcher; M P Dierich; D Falke
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

10.  Antiviral drugs from the nucleoside analog family block volume-activated chloride channels.

Authors:  M Gschwentner; A Susanna; E Wöll; M Ritter; U O Nagl; A Schmarda; A Laich; G M Pinggera; H Ellemunter; H Huemer
Journal:  Mol Med       Date:  1995-05       Impact factor: 6.354
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