Literature DB >> 6266355

Trauma affects cyclic AMP and DNA levels at injured and non-injured distal oral mucosal sites.

A S Fine, R W Egnor, S S Stahl.   

Abstract

Experiments in rats were conducted to test the hypothesis that gingival trauma affects cyclic AMP and DNA levels at the gingival wound, and non-injured distal (gingival, palatal) sites. Cyclic AMP and DNA levels rose and fell in a cyclic fashion during the time (0.5-24 h) periods analyzed. Significant increases in cAMP levels occurred at 8 and 20 h and at 8 and 16 h, respectively, at the wound and non-injured palatal site, peripheral to the wound. Similar increases (not significant) in cAMP levels were also noted at the non-injured gingival contralateral site at the same time intervals. DNA distributions were found to be significantly greater 10 and 16 h after injury at the gingival wound, and distal non-injured gingival and palatal sites.

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Year:  1981        PMID： 6266355     DOI： 10.1007/bf00417144

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  22 in total

1.  CHEMISTRY OF INFLAMMATION.

Authors:  J C HOUCK
Journal:  Ann N Y Acad Sci       Date:  1963-11-25       Impact factor: 5.691

2.  FLUOROMETRIC ULTRAMICROANALYSIS OF DEOXYRIBONUCLEIC ACID IN HUMAN SKIN.

Authors:  P SANTOIANNI; M AYALA
Journal:  J Invest Dermatol       Date:  1965-08       Impact factor: 8.551

3.  Autoradiographic assessment of the distal response to gingival injury.

Authors:  E A Tonna; S S Stahl; J Slywka
Journal:  J Periodontal Res       Date:  1977-05       Impact factor: 4.419

4.  Modulation of gingival cAMP levels by tissue inflammation.

Authors:  M F Grower; D Chandler
Journal:  J Periodontal Res       Date:  1979-01       Impact factor: 4.419

5.  Studies of the chemical composition of a healing skin wound in rats, and of the concentrations of some constituents of tissues distant from the healing wound.

Authors:  J Candlish; N Chandra
Journal:  Biochem J       Date:  1967-03       Impact factor: 3.857

6.  The cyclic AMP-dependent initiation of DNA synthesis by T51B rat liver epithelioid cells.

Authors:  A L Boynton; J F Whitfield
Journal:  J Cell Physiol       Date:  1979-10       Impact factor: 6.384

7.  A new simple method for separation of adenosine 3',5'-cyclic monophosphate from other nucleotides and its use in the assay of adenyl cyclase.

Authors:  J Ramachandran
Journal:  Anal Biochem       Date:  1971-09       Impact factor: 3.365

8.  Studies on the biology of collagen during wound healing. 3. Dynamic metabolism of scar collagen and remodeling of dermal wounds.

Authors:  J W Madden; E E Peacock
Journal:  Ann Surg       Date:  1971-09       Impact factor: 12.969

9.  Adrenergic antagonists, and a possible link between the increase in cyclic adenosine 3',5'-monophosphate and DNA synthesis during liver regeneration.

Authors:  J P MacManus; B M Braceland; T Youdale; J F Whitfield
Journal:  J Cell Physiol       Date:  1973-10       Impact factor: 6.384

Review 10.  The positive control of cell proliferation by the interplay on calcium ions and cyclic nucleotides. A review.

Authors:  J F Whitfield; J P MacManus; R H Rixon; A L Boynton; T Youdale; S Swierenga
Journal:  In Vitro       Date:  1976-01
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