Literature DB >> 6265595

Transposable gentamicin resistance in IncW plasmids from Hammersmith Hospital.

M E Nugent, N Datta.   

Abstract

A transposon, Tn733, encoding the gentamicin acetyltransferase AAC(3) was found on two gentamicin R plasmids of IncW at Hammersmith Hospital. Transposon TN733 has a molecular mass of 5.8 megadaltons and gives a characteristic 2.4 megadalton fragment on digestion with EcoRI. The appearance of gentamicin resistance on a transposon will increase the chances of spread of this gene.

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Year:  1980        PMID： 6265595     DOI： 10.1099/00221287-121-1-259

Source DB:  PubMed          Journal:  J Gen Microbiol        ISSN： 0022-1287


  2 in total

1.  Incidence of metal and antibiotic resistance in Pseudomonas spp. from the river water, agricultural soil irrigated with wastewater and groundwater.

Authors:  Abdul Malik; Asma Aleem
Journal:  Environ Monit Assess       Date:  2010-09-21       Impact factor: 2.513

2.  Plasmid macroevolution in a nosocomial environment: demonstration of a persistent molecular polymorphism and construction of a cladistic phylogeny on the basis of restriction data.

Authors:  S C Lee; D N Gerding; P P Cleary
Journal:  Mol Gen Genet       Date:  1984
  2 in total

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