| Literature DB >> 6265382 |
J Wright, L A Falk, L G Wolfe, F Deinhardt.
Abstract
An attenuated strain of Herpesvirus saimiri (A-HVS) induced a persistent, latent infection in common marmosets. Virus was recovered from circulating lymphocytes of infected animals and antibody response to virus-specified antigens was demonstrated over 3-12 months PI. A-HVS-infected common marmosets and animals without previous A-HVS exposure were challenged with oncogenic HVS (125-825 PFU); marmosets without A-HVS infection developed malignant lymphoproliferative disease and died 3 weeks PI whereas all persistently-infected animals have survived 38-43 months post challenge.Entities:
Mesh:
Year: 1980 PMID: 6265382 DOI: 10.1002/ijc.2910260413
Source DB: PubMed Journal: Int J Cancer ISSN: 0020-7136 Impact factor: 7.396