Literature DB >> 626484

Consequence of cerulenin-released beta-lactamase in clinical coliforms.

T K Choudhury.   

Abstract

Periplasmic beta-lactamase of certain clinical coliforms was released, without affecting cell viability, by perturbation of the outer membrane utilizing the fatty acid-mimicking antibiotic cerulenin. Release of such compartmentalized beta-lactamase, at high population density, seems to provide an extra margin of resistance to the organisms against cephaloridine.

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Year:  1978        PMID: 626484      PMCID: PMC352194          DOI: 10.1128/AAC.13.1.121

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  7 in total

Review 1.  Metabolism and function of the membrane phospholipids of Escherichia coli.

Authors:  J E Cronan; P R Vagelos
Journal:  Biochim Biophys Acta       Date:  1972-02-14

2.  Origin and function of penicillinase: a problem in biochemical evolution.

Authors:  M R Pollock
Journal:  Br Med J       Date:  1967-10-14

3.  Peptidoglycan transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reactions.

Authors:  J L Strominger; K Izaki; M Matsuhashi; D J Tipper
Journal:  Fed Proc       Date:  1967 Jan-Feb

4.  Lipid composition and permeability of liposomes.

Authors:  J de Gier; J G Mandersloot; L L van Deenen
Journal:  Biochim Biophys Acta       Date:  1968-06-11

Review 5.  The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis.

Authors:  S Omura
Journal:  Bacteriol Rev       Date:  1976-09

6.  Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.

Authors:  C H O'Callaghan; A Morris; S M Kirby; A H Shingler
Journal:  Antimicrob Agents Chemother       Date:  1972-04       Impact factor: 5.191

7.  Inhibition of lipid synthesis in Escherichia coli cells by the antibiotic cerulenin.

Authors:  I Goldberg; J R Walker; K Bloch
Journal:  Antimicrob Agents Chemother       Date:  1973-05       Impact factor: 5.191

  7 in total

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