| Literature DB >> 626484 |
Abstract
Periplasmic beta-lactamase of certain clinical coliforms was released, without affecting cell viability, by perturbation of the outer membrane utilizing the fatty acid-mimicking antibiotic cerulenin. Release of such compartmentalized beta-lactamase, at high population density, seems to provide an extra margin of resistance to the organisms against cephaloridine.Entities:
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Year: 1978 PMID: 626484 PMCID: PMC352194 DOI: 10.1128/AAC.13.1.121
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191