| Literature DB >> 6263793 |
Abstract
Infection of mice with herpes simplex virus type 2 (HSV 2) stimulated natural killer (NK) cells in a variety of inbred mouse strains including athymic nude mice. Essentially all mouse strains tested exhibited high NK activity on day four after virus inoculation. Assayed 24 hours after infection, SWR/J, AKR/J, SJL/J and C57B1/10J mice were low or negative for these non-virus-specific cytotoxic responses. Whereas the first two mouse strains were most sensitive to the lethal effects of HSV 2, the latter two were highly resistant. Three lines with intermediate susceptibility and three highly resistant strains were all efficient with regard to early NK-cell.Entities:
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Year: 1981 PMID： 6263793 DOI： 10.1016/S0171-2985(81)80007-1
Source DB: PubMed Journal: Immunobiology ISSN： 0171-2985 Impact factor: 3.144