| Literature DB >> 6263357 |
A Danchin, L Dondon, E Joseph, A Ullmann.
Abstract
Using specific mutants exhibiting altered translational rates we found that when the rate of protein synthesis is reduced the polarity of the lactose and galactose operons is increased. This polarity is in part relieved by cyclic AMP. On the basis of in vitro hybridization experiments were propose that the cyclic AMP-CAP complex and the ribosomes display similar functions, namely destabilization of the RNA-DNA hybrid formed during transcription.Entities:
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Year: 1981 PMID： 6263357 DOI： 10.1016/s0300-9084(81)80015-6
Source DB: PubMed Journal: Biochimie ISSN： 0300-9084 Impact factor: 4.079