The effect of added bran to the diet on the saturation of bilein people without gallstones.

Bran was added to the diet of eleven volunteers without gallstones, and its effect on bile saturation, bile acid profile in bile, and serum cholesterol and triglycerides was determined. Bile cholesterol saturation was decreased after two months of feeding bran to those female subjects who had supersaturated bile. Bran may be effective in decreasing the lithogenic potential of bile in people without gallstones, and further studies on its place in the prevention of gallstones in susceptible individuals are indicated.